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Difference between revisions of "Testis"
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→Sertoli cell tumour: +SCN
(→Embryonal carcinoma: wikify) |
(→Sertoli cell tumour: +SCN) |
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**AKA ''MART-1''. | **AKA ''MART-1''. | ||
**Expressed in melanoma, adrenal tissue, steroid-secreting tumours. | **Expressed in melanoma, adrenal tissue, steroid-secreting tumours. | ||
==Sertoli cell nodule== | |||
===General=== | |||
*[[AKA]] Pick's adenoma, AKA testicular tubular adenoma, AKA tubular adenoma of the testis. | |||
*Benign proliferation of Sertoli cells - associated with cryptorchidism (undescended testis). | |||
*Not composed of a clonal cell population, i.e. ''not'' neoplastic; thus, technically, should not be called an ''adenoma''.<ref name=Ref_DCHH227>{{Ref DCHH|227}}</ref> | |||
===Microscopic=== | |||
Features:<ref name=Ref_DCHH227>{{Ref DCHH|227}}</ref><ref>{{cite journal |author=Ricco R, Bufo P |title=[Histologic study of 3 cases of so-called tubular adenoma of the testis] |language=Italian |journal=Boll. Soc. Ital. Biol. Sper. |volume=56 |issue=20 |pages=2110–5 |year=1980 |month=October |pmid=6109541 |doi= |url=}}</ref> | |||
*Unencapsulated nodules composed of well-formed tubules. | |||
**May contain eosinophilic (hyaline) blob in lumen (centre). | |||
*Cells - vaguely resemble immature Sertoli cells: | |||
**Bland hyperchromatic oval/round nuclei that are stratified. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_high_mag.jpg Sertoli cell nodule - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_nodule_low_mag.jpg Sertoli cell nodule - low mag. (WC)]. | |||
==Sertoli cell tumour== | ==Sertoli cell tumour== | ||