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'''Reactive changes''' is a commonly used term in [[pathology]] that implies: | '''Reactive changes''' is a commonly used term in [[pathology]] that implies: | ||
# Inflammation. | # Inflammation. | ||
# Nuclear changes compatible with inflammation. | # Nuclear changes compatible with inflammation. | ||
# The absence of both neoplasia and the suspicious of neoplasia, i.e. benignancy. | |||
'''Reactive inflammatory changes''' and ''inflammatory changes''' can be considered synonyms. | |||
==General== | ==General== | ||
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*Inflammatory processes. | *Inflammatory processes. | ||
*Repair. | *Repair. | ||
*Neoplastic processes. | *Neoplastic processes, i.e. pre-cancerous conditions (e.g. dysplasia) and [[cancer]]. | ||
Significance of nuclear changes in inflammation: | Significance of nuclear changes in inflammation: | ||
*The line between a reactive process and a neoplastic process may be fuzzy, i.e. it may be very difficult to be certain whether something is benign or malignant. | *The line between a reactive process and a neoplastic process may be fuzzy, i.e. it may be very difficult to be certain whether something is benign or [[malignant]]. | ||
Consequence: | Consequence: | ||
*In the context of inflammation, nuclear changes are typically present and the threshold for calling suspicious or malignancy is typically higher. | *In the context of inflammation, nuclear changes are typically present and the threshold for calling ''suspicious for malignancy'' or ''[[malignancy]]'' is typically higher. | ||
==Microscopic== | ==Microscopic== |
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