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Relevance: | Relevance: | ||
*Increased risk of vasa previa.<ref name=pmid20872421>{{cite journal |author=Hasegawa J, Farina A, Nakamura M, ''et al.'' |title=Analysis of the ultrasonographic findings predictive of vasa previa |journal=Prenat. Diagn. |volume=30 |issue=12-13 |pages=1121–5 |year=2010 |month=December |pmid=20872421 |doi=10.1002/pd.2618 |url=}}</ref> | *Increased risk of vasa previa.<ref name=pmid20872421>{{cite journal |author=Hasegawa J, Farina A, Nakamura M, ''et al.'' |title=Analysis of the ultrasonographic findings predictive of vasa previa |journal=Prenat. Diagn. |volume=30 |issue=12-13 |pages=1121–5 |year=2010 |month=December |pmid=20872421 |doi=10.1002/pd.2618 |url=}}</ref> | ||
==Knots== | |||
===General=== | |||
*Prevalence ~1.25%.<ref name=pmid12012287>{{cite journal |author=Airas U, Heinonen S |title=Clinical significance of true umbilical knots: a population-based analysis |journal=Am J Perinatol |volume=19 |issue=3 |pages=127–32 |year=2002 |month=April |pmid=12012287 |doi=10.1055/s-2002-25311 |url=}}</ref><ref name=Ref_WMSP>{{Ref WMSP|464}}</ref> | |||
*Increase risk of stillbirth; odds ratio 3.93.<ref name=pmid12012287/> | |||
===Gross=== | |||
Work-up:<ref name=Ref_WMSP>{{Ref WMSP|464}}</ref> | |||
*Diameter measures and colour on both sides of the knot. | |||
*Knot should be untied to assess for deformation of Wharton's jelly. | |||
*Sections from both sides of the knot - to look for thrombi. | |||
===Microscopic=== | |||
Features: | |||
*+/-Thrombi. | |||
**Fibrin deposition. | |||
*+/-Lines of Zahn. | |||
Images: | |||
*[http://library.med.utah.edu/WebPath/ATHHTML/ATH031.html Lines of Zahn (utah.edu)]. | |||
*[http://pathhsw5m54.ucsf.edu/case9/image94.html Lines of Zahn (ucsf.edu)]. | |||
=Twin placentas= | =Twin placentas= |
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