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Difference between revisions of "Neuropathology tumours"
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→Gliosarcoma
(→Astrocytomas: +gliosarcoma) |
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| Line 178: | Line 178: | ||
==Gliosarcoma== | ==Gliosarcoma== | ||
===General=== | ===General=== | ||
*Considered to be a variant of glioblastoma by WHO.<ref name=pmid19618114>{{cite journal |author=Han SJ, Yang I, Tihan T, Prados MD, Parsa AT |title=Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity |journal=J. Neurooncol. |volume=96 |issue=3 |pages=313–20 |year=2010 |month=February |pmid=19618114 |pmc=2808523 |doi=10.1007/s11060-009-9973-6 |url=}}</ref> | |||
*Gliosarcoma = glioblastoma + sarcomatous component.<ref name=pmid20415184>{{cite journal |author=Ayadi L, Charfi S, Khabir A, ''et al.'' |title=[Cerebral gliosarcoma: clinico-pathologic study of 8 cases] |language=French |journal=Tunis Med |volume=88 |issue=3 |pages=142–6 |year=2010 |month=March |pmid=20415184 |doi= |url=}}</ref> | *Gliosarcoma = glioblastoma + sarcomatous component.<ref name=pmid20415184>{{cite journal |author=Ayadi L, Charfi S, Khabir A, ''et al.'' |title=[Cerebral gliosarcoma: clinico-pathologic study of 8 cases] |language=French |journal=Tunis Med |volume=88 |issue=3 |pages=142–6 |year=2010 |month=March |pmid=20415184 |doi= |url=}}</ref> | ||
*Usual location (like glioblastoma): temporal lobe. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Glioblastoma. | *[[Glioblastoma]]. | ||
*Sarcomatous component (one of the following):<ref name=pmid20415184/> | *Sarcomatous component (one of the following):<ref name=pmid19618114/><ref name=pmid20415184/> | ||
** | **Fibroblastic. | ||
** | **Cartilaginous. | ||
** | **Osseous. | ||
**Smooth muscle. | |||
**Striated muscle. | |||
**Adipocyte. | |||
Image: [http://commons.wikimedia.org/wiki/File:Gliosarcoma_Histopathology_200x_EVG.jpg Gliosarcoma - elastic von Gieson (WC)]. | Image: [http://commons.wikimedia.org/wiki/File:Gliosarcoma_Histopathology_200x_EVG.jpg Gliosarcoma - elastic von Gieson (WC)]. | ||