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(→KRAS mutation: +main) |
m (→IHC) |
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*'''Loss of nuclear staining''' in nuclei of the tumour ''implies'' a mutation. | *'''Loss of nuclear staining''' in nuclei of the tumour ''implies'' a mutation. | ||
**Nuclear staining = normal. | **Nuclear staining = normal. | ||
* Patchy MSH6 is considered normal.{{fact}}<!-- possibly PMID 21297438 --> | |||
MSI staining loss patterns:<ref name=pmid20632815/> | MSI staining loss patterns:<ref name=pmid20632815/> |
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