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'''Rhinoscleroma''' is a rare infectious condition of the [[head and neck pathology|head and neck]]. | |||
==General== | |||
*Caused by ''Klebsiella rhinoscleromatis''. | |||
*Nose involved +95% of the time.<ref name=pmid17359555>{{Cite journal | last1 = Chan | first1 = TV. | last2 = Spiegel | first2 = JH. | title = Klebsiella rhinoscleromatis of the membranous nasal septum. | journal = J Laryngol Otol | volume = 121 | issue = 10 | pages = 998-1002 | month = Oct | year = 2007 | doi = 10.1017/S0022215107006421 | PMID = 17359555 }}</ref> | |||
==Gross== | |||
*Nasal mass - may be deforming. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Wolkowitsch1.jpg Rhinoscleroma (WC)]. | |||
==Microscopic== | |||
Features:<ref>URL: [http://www.brown.edu/Courses/Digital_Path/systemic_path/hn/rhinoscleroma2.html http://www.brown.edu/Courses/Digital_Path/systemic_path/hn/rhinoscleroma2.html]. Accessed on: 18 January 2012.</ref> | |||
*Macrophages - clear-to-foamy cytoplasm. | |||
*Lymphocytes. | |||
*Plasma cells. | |||
DDx: | |||
*[[Rosai-Dorfman disease]].<ref>{{cite journal |author=Iyer VK, Handa KK, Sharma MC |title=Variable extent of emperipolesis in the evolution of Rosai Dorfman disease: Diagnostic and pathogenetic implications |journal=J Cytol |volume=26 |issue=3 |pages=111–6 |year=2009 |month=July |pmid=21938169 |pmc=3168012 |doi=10.4103/0970-9371.59398 |url=}}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Rhinoscleroma_-_intermed_mag.jpg | Rhinoscleroma - intermed. mag. (WC) | |||
Image:Rhinoscleroma_-_high_mag.jpg | Rhinoscleroma - high mag. (WC) | |||
Image:Rhinoscleroma_-_very_high_mag.jpg | Rhinoscleroma - very high mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.brown.edu/Courses/Digital_Path/systemic_path/hn/rhinoscleroma2.html Rhinoscleroma (brown.edu)]. | |||
*[http://www.jameswpattersonmd.com/images/pages/rhinoscleroma_mic324.jpg Rhinoscleroma (jameswpattersonmd.com)].<ref>URL: [http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434 http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434]. Accessed on: 21 February 2012.</ref> | |||
==Stains== | |||
*Warthin-Starry stain +ve (rod-shaped organisms). | |||
*[[Dieterle stain]] +ve (rod-shaped organisms). | |||
==See also== | |||
*[[Head and neck pathology]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Head and neck pathology]] |
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