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Difference between revisions of "Chondro-osseous tumours"
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Chondro-osseous tumours (view source)
Revision as of 06:23, 12 December 2010
, 06:23, 12 December 2010→Osteosarcoma: +images
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
* | *Cells with malignant features (e.g. nuclear membrane irregularities, marked nuclear size differences, mitoses) surrounded by delicate strands of osteoid. | ||
**Osteoid on H&E: pink, homogenous, "glassy". | **Osteoid on H&E: pink, homogenous, "glassy". | ||
**Tumours typically very cellular - when compared to normal bone. | **Tumours typically very cellular - when compared to normal bone. | ||
*Large (multinucleated) osteoclast-like giant cells may be seen.<ref>{{cite journal |author=Papalas JA, Balmer NN, Wallace C, Sangueeza OP |title=Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review |journal=Am J Dermatopathol |volume=31 |issue=4 |pages=379-83 |year=2009 |month=June |pmid=19461244 |doi=10.1097/DAD.0b013e3181966747 |url=}}</ref> | *Large (multinucleated) osteoclast-like giant cells may be seen.<ref>{{cite journal |author=Papalas JA, Balmer NN, Wallace C, Sangueeza OP |title=Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review |journal=Am J Dermatopathol |volume=31 |issue=4 |pages=379-83 |year=2009 |month=June |pmid=19461244 |doi=10.1097/DAD.0b013e3181966747 |url=}}</ref> | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Osteosarcoma_-_intermed_mag.jpg Osteosarcoma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Osteosarcoma_-_very_high_mag.jpg Osteosarcoma - very high mag. (WC)]. | |||
=Other= | =Other= | ||