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Difference between revisions of "Adenocarcinoma of the lung"
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| Caption = Lung adenocarcinoma, mucinous. [[H&E stain]]. | | Caption = Lung adenocarcinoma, mucinous. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = nuclear atypia, eccentrically placed nuclei, usu. abundant cytoplasm (classically with mucin vacuoles), often conspicuous [[nucleoli]], +/-[[nuclear pseudoinclusions]] | | Micro = +/-nuclear atypia (may be absent in mucinous tumours), eccentrically placed nuclei, usu. abundant cytoplasm (classically with mucin vacuoles), often conspicuous [[nucleoli]], +/-[[nuclear pseudoinclusions]] | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[atypical adenomatous hyperplasia of the lung]], adenocarcinoma in situ, [[squamous cell carcinoma of the lung]], [[small cell carcinoma of the lung]], [[non-small cell lung carcinoma]], [[malignant mesothelioma]], [[Metastasis|metastatic]] [[adenocarcinoma]] (esp. [[colorectal adenocarcinoma]], breast adenocarcinoma ([[invasive ductal carcinoma of the breast]], [[invasive lobular carcinoma]])) | | LMDDx = [[atypical adenomatous hyperplasia of the lung]], adenocarcinoma in situ, [[squamous cell carcinoma of the lung]], [[small cell carcinoma of the lung]], [[non-small cell lung carcinoma]], [[malignant mesothelioma]], [[Metastasis|metastatic]] [[adenocarcinoma]] (esp. [[colorectal adenocarcinoma]], breast adenocarcinoma ([[invasive ductal carcinoma of the breast]], [[invasive lobular carcinoma]])) | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Nuclear atypia. | *+/-Nuclear atypia - '''important'''. | ||
**May be absent in mucinous tumours - may look similar to foveolar epithelium. | |||
*Eccentrically placed nuclei. | *Eccentrically placed nuclei. | ||
*Abundant cytoplasm - classically with mucin vacuoles. | *Abundant cytoplasm - classically with mucin vacuoles. | ||
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***[[Invasive ductal carcinoma of the breast]]. | ***[[Invasive ductal carcinoma of the breast]]. | ||
***[[Invasive lobular carcinoma]]. | ***[[Invasive lobular carcinoma]]. | ||
**Other carcinomas. | |||
*Carcinomas of the bronchial glands, e.g. [[adenoid cystic carcinoma]]. | |||
===Images=== | ===Images=== | ||