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Difference between revisions of "Intradermal nevus"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Intradermal nevus -- intermed mag.jpg | |||
| Width = | |||
| Caption = Intradermal nevus. [[H&E stain]]. | |||
| Synonyms = intradermal melanocytic nevus | |||
| Micro = nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement | |||
| Subtypes = | |||
| LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[compound nevus]], [[dysplastic nevus]], [[skin tag]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = pigment skin lesion, usu. small, regular border, no irregularity in pigmentation | |||
| Grossing = | |||
| Site = [[skin]] - see ''[[melanocytic lesions]]'' and ''[[common nevus]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = pigmented skin lesions | |||
| Tx = none required, may be excised for cosmetic reasons | |||
}} | |||
'''Intradermal nevus''' (abbreviated '''IDN'''), also '''intradermal melanocytic nevus''', is a common benign [[melanocytic lesion]]. | |||
The ''intradermal nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''. | |||
==General== | |||
*Benign. | |||
*Common. | |||
*Think ''[[melanoma]]''. | |||
Clinical: | |||
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large). | |||
==Microscopic== | |||
Features: | |||
*Symmetrical lesion. | |||
*"Matures" with depth. | |||
**Less cellular with depth. | |||
**Less nuclear atypia with depth. | |||
**Smaller cells with depth. | |||
**Smaller nests with depth. | |||
*Rare mitoses (superficial). | |||
**No deep mitoses. | |||
*No destruction of surrounding structures. | |||
*No nucleoli. | |||
*In the dermis only - '''key feature'''. | |||
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi = | PMID = 9810886 }}</ref> | |||
DDx: | |||
*[[Malignant melanoma]] (nevoid). | |||
*[[Dysplastic nevus]]. | |||
*[[Junctional nevus]]. | |||
*[[Compound nevus]]. | |||
*[[Skin tag]]. | |||
===Images=== | |||
<gallery> | |||
Image: Intradermal nevus -- very low mag.jpg | IDN - very low mag. | |||
Image: Intradermal nevus -- low mag.jpg | IDN - low mag. | |||
Image: Intradermal nevus -- intermed mag.jpg | IDN - intermed. mag. | |||
Image: Intradermal nevus -- high mag.jpg | IDN - high mag. | |||
Image: Intradermal nevus -- very high mag.jpg | IDN - very high mag. | |||
</gallery> | |||
==Sign out== | |||
==See also== | |||
*[[Melanocytic lesions]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | |||
[[Category:Melanocytic lesions]] | |||