Difference between revisions of "Uterine tumours"

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Uterine tumours (view source)

Revision as of 02:06, 20 March 2014

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→‎Atypical polypoid adenomyoma of the uterus: split out
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*Abbreviated ''APA''.
*Abbreviated ''APA''.
*[[AKA]] ''atypical polypoid adenomyoma''.
*[[AKA]] ''atypical polypoid adenomyoma''.
===General===
{{Main|Atypical polypoid adenomyoma of the uterus}}
*Very rare.<ref name=pmid21684185>{{Cite journal  | last1 = Terada | first1 = T. | title = Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases. | journal = Ann Diagn Pathol | volume = 15 | issue = 5 | pages = 338-41 | month = Oct | year = 2011 | doi = 10.1016/j.anndiagpath.2011.03.008 | PMID = 21684185 }}</ref>
*Benign.<ref name=pmid17050990/>
*Reproductive age women.
 
===Gross===
*Lower uterine segment.
 
===Microscopic===
Features:<ref name=pmid17050990>{{Cite journal  | last1 = Jakus | first1 = S. | last2 = Edmonds | first2 = P. | last3 = Dunton | first3 = C. | last4 = Holland | first4 = G. | title = Atypical polypoid adenomyoma mimicking cervical adenocarcinoma. | journal = J Low Genit Tract Dis | volume = 6 | issue = 1 | pages = 33-8 | month = Jan | year = 2002 | doi =  | PMID = 17050990 }}</ref>
*Glands with irregular (non-ovoid) shapes.
*Benign smooth muscle around the glands - '''key feature'''.
*Morular squamous metaplasia - balls of squamous cells - very common.
*Nuclear atypia (mild).
 
DDx:
*[[Endometrioid endometrial carcinoma]].
*[[Endometrium with squamous morules]] - more common.
*Endocervical adenocarcinoma.
 
====Images====
<gallery>
Image:Atypical_polypoid_adenomyoma_-_intermed_mag.jpg | APA - intermed. mag. (WC)
Image:Atypical_polypoid_adenomyoma_-_high_mag.jpg | APA - high mag. (WC)
Image:Atypical_polypoid_adenomyoma_-_very_high_mag.jpg | APA - very high mag. (WC)
</gallery>
www:
*[http://www.pathologypics.com/PictView.aspx?ID=1220 APA (pathologypics.com)].
 
===IHC===
Features (glandular component):<ref name=pmid21684185/>
*AE1/AE3 +ve.
*CK7 +ve.
*ER +ve.
*PR +ve.
 
Significant negative (glandular component):<ref name=pmid21684185/>
*[[CK20]] -ve.
*CEA -ve.
 
===Sign out===
<pre>
ENDOMETRIUM, CURETTAGE:
- ATYPICAL POLYPOID ADENOMYOMA.
 
COMMENT:
Atypical polypoid adenomyomas are considered to be benign lesions; however,
they may persist or recur in up to half of patients.
</pre>


=See also=
=See also=
Michael
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