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Difference between revisions of "Serous cystadenoma of the ovary"
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Serous cystadenoma of the ovary (view source)
Revision as of 03:20, 7 June 2016
, 03:20, 7 June 2016→Images
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| Other = | | Other = | ||
| ClinDDx = other [[ovarian tumours]] | | ClinDDx = other [[ovarian tumours]] | ||
| Tx = cystectomy or | | Tx = cystectomy or oophorectomy | ||
}} | }} | ||
'''Serous cystadenoma of the ovary''' is a common benign finding in the [[ovary]]. | '''Serous cystadenoma of the ovary''' is a common benign finding in the [[ovary]]. | ||
It is also known as ''ovarian [[serous cystadenoma]]''. It is unrelated | It is also known as ''ovarian [[serous cystadenoma]]''. It is unrelated the [[pancreatic serous cystadenoma]]. | ||
'''Serous cystadenofibroma''' and '''[[adenofibroma]] of the ovary''' can be considered variants, and are also dealt with in this article. | '''Serous cystadenofibroma''' and '''[[adenofibroma]] of the ovary''' can be considered variants, and are also dealt with in this article. | ||
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Cystadenofibroma and adenofibroma:<ref name=pmid23171527>{{Cite journal | last1 = Takeuchi | first1 = M. | last2 = Matsuzaki | first2 = K. | last3 = Harada | first3 = M. | title = Ovarian adenofibromas and cystadenofibromas: magnetic resonance imaging findings including diffusion-weighted imaging. | journal = Acta Radiol | volume = 54 | issue = 2 | pages = 231-6 | month = Mar | year = 2013 | doi = 10.1258/ar.2012.120516 | PMID = 23171527 }}</ref> | Cystadenofibroma and adenofibroma:<ref name=pmid23171527>{{Cite journal | last1 = Takeuchi | first1 = M. | last2 = Matsuzaki | first2 = K. | last3 = Harada | first3 = M. | title = Ovarian adenofibromas and cystadenofibromas: magnetic resonance imaging findings including diffusion-weighted imaging. | journal = Acta Radiol | volume = 54 | issue = 2 | pages = 231-6 | month = Mar | year = 2013 | doi = 10.1258/ar.2012.120516 | PMID = 23171527 }}</ref> | ||
*Solid or solid and cystic. | *Solid or solid and cystic. | ||
Note: | |||
*Cystic lesions must be >=1 cm in size, smaller lesions are ''surface epithelial inclusion cysts''.<ref name=Ref_GP384>{{Ref GP|384}}</ref> | |||
===Image=== | ===Image=== | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=Ref_GP396>{{Ref GP|396}}</ref> | ||
*Simple epithelium | *Simple epithelium - '''key feature''' - usually with cilia. | ||
**Cell morphology: columnar, cuboidal or flatted. | **Cell morphology: columnar, cuboidal or flatted. | ||
*Absent or minimal [[nuclear atypia]]. | |||
*+/-Rare tufting. | |||
*+/-Non-branching papillae. | |||
*+/-Rare mitoses. | |||
Note: | Note: | ||
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DDx: | DDx: | ||
*Cortical inclusion cyst - see ''[[mesothelial inclusion cyst]]''. | *Cortical inclusion cyst - <1 cm in size, see ''[[mesothelial inclusion cyst]]''. | ||
*[[Ovarian serous borderline tumour]]. | *[[Ovarian serous borderline tumour]] - branching papillae, tufting, mitoses, nuclear atypia. | ||
Note - the following may be lumped with this entity: | Note - the following may be lumped with this entity: | ||
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===Images=== | ===Images=== | ||
====Serous cystadenoma==== | |||
<gallery> | <gallery> | ||
Image: Ovarian serous cystadenoma - alt -- low mag.jpg | OSC - low mag. | Image: Ovarian serous cystadenoma - alt -- low mag.jpg | OSC - low mag. | ||
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Image: Ovarian serous cystadenoma -- extremely high mag.jpg | OSC - extremely high mag. | Image: Ovarian serous cystadenoma -- extremely high mag.jpg | OSC - extremely high mag. | ||
</gallery> | </gallery> | ||
www | ====Serous cystadenofibroma==== | ||
<gallery> | |||
Image: Serous cystadenofibroma -- very low mag.jpg | SCAF - very low mag. | |||
Image: Serous cystadenofibroma -- low mag.jpg | SCAF - low mag. | |||
Image: Serous cystadenofibroma -- intermed mag.jpg | SCAF - intermed. mag. | |||
Image: Serous cystadenofibroma -- high mag.jpg | SCAF - high mag. | |||
</gallery> | |||
=====www===== | |||
*[http://www.webpathology.com/image.asp?case=525&n=4 Serous cystadenofibroma - low mag. (webpathology.com)]. | *[http://www.webpathology.com/image.asp?case=525&n=4 Serous cystadenofibroma - low mag. (webpathology.com)]. | ||
*[http://www.webpathology.com/image.asp?n=5&Case=525 Serous cystadenofibroma - high mag. (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=5&Case=525 Serous cystadenofibroma - high mag. (webpathology.com)]. | ||
==IHC== | |||
Features:<ref name=Ref_GP396/> | |||
*CK7 +ve. | |||
*EMA +ve. | |||
*WT1 +ve. | |||
*CK20 -ve. | |||
==Sign out== | ==Sign out== | ||
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lesion is best classified as benign with focal atypia. | lesion is best classified as benign with focal atypia. | ||
</pre> | </pre> | ||
===Micro=== | |||
The sections show fibrous tissue consistent with a cyst wall lined by a simple columnar to flat epithelium, focally with cilia. | |||
Cautery is present imparting a pseudostratified appearance focally. No definite papillae or definite tufting is apparent. No significant nuclear atypia is seen. Mitotic activity is not apparent. | |||
==See also== | ==See also== | ||