Difference between revisions of "Juvenile granulosa cell tumour"

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==General==
==General==
*May secrete estrogen.
*Uncommon.<ref name=pmid23033282>{{Cite journal  | last1 = Oztekin | first1 = D. | last2 = Kurt | first2 = S. | last3 = Camuzcuoglu | first3 = H. | last4 = Balsak | first4 = D. | last5 = Dicle | first5 = N. | last6 = Tinar | first6 = S. | title = Granulosa cell tumors of the ovary: review of 43 cases. | journal = J BUON | volume = 17 | issue = 3 | pages = 461-4 | month = | year = | doi =  | PMID = 23033282 }}</ref>
**May present with endometrial pathology, e.g. [[endometrial hyperplasia]] ''or'' endometrioid [[endometrial carcinoma]].
**May present as precocious puberty.<ref name=pmid21526089>{{Cite journal  | last1 = Hashemipour | first1 = M. | last2 = Moaddab | first2 = MH. | last3 = Nazem | first3 = M. | last4 = Mahzouni | first4 = P. | last5 = Salek | first5 = M. | title = Granulosa cell tumor in a six-year-old girl presented as precocious puberty. | journal = J Res Med Sci | volume = 15 | issue = 4 | pages = 240-2 | month = Jul | year = 2010 | doi =  | PMID = 21526089 }}</ref>
*Reported in males.<ref>URL: [http://path.upmc.edu/cases/case631.html http://path.upmc.edu/cases/case631.html]. Accessed on: 26 January 2012.</ref>
*Reported in males.<ref>URL: [http://path.upmc.edu/cases/case631.html http://path.upmc.edu/cases/case631.html]. Accessed on: 26 January 2012.</ref>
*Uncommon.<ref name=pmid23033282>{{Cite journal  | last1 = Oztekin | first1 = D. | last2 = Kurt | first2 = S. | last3 = Camuzcuoglu | first3 = H. | last4 = Balsak | first4 = D. | last5 = Dicle | first5 = N. | last6 = Tinar | first6 = S. | title = Granulosa cell tumors of the ovary: review of 43 cases. | journal = J BUON | volume = 17 | issue = 3 | pages = 461-4 | month = | year = | doi =  | PMID = 23033282 }}</ref>
 
May secrete estrogen - can present with:
*Endometrial pathology, e.g. [[endometrial hyperplasia]] ''or'' endometrioid [[endometrial carcinoma]].
*Precocious puberty.<ref name=pmid21526089>{{Cite journal  | last1 = Hashemipour | first1 = M. | last2 = Moaddab | first2 = MH. | last3 = Nazem | first3 = M. | last4 = Mahzouni | first4 = P. | last5 = Salek | first5 = M. | title = Granulosa cell tumor in a six-year-old girl presented as precocious puberty. | journal = J Res Med Sci | volume = 15 | issue = 4 | pages = 240-2 | month = Jul | year = 2010 | doi =  | PMID = 21526089 }}</ref>
 
Prognosis - granulosa cell tumours (adult and juvenile):<ref name=pmid23033282/>
*Low-stage: 97% five year survival.
*High-stage: 67% five year survival.


==Gross==
==Gross==
48,830

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