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Difference between revisions of "Atypical teratoid/rhabdoid tumour"
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Atypical teratoid/rhabdoid tumour (view source)
Revision as of 03:27, 17 February 2014
, 03:27, 17 February 2014→IHC
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==IHC== | ==IHC== | ||
*BAF-47 -ve ([[AKA]] ''INI1'', [[AKA]] ''SMARCB1'' - the HGNC symbol<ref name=omim601607>{{OMIM|601607}}</ref>) - virtually diagnostic. | *BAF-47 -ve ([[AKA]] ''INI1'', [[AKA]] ''SMARCB1'' - the HGNC symbol<ref name=omim601607>{{OMIM|601607}}</ref>) - virtually diagnostic (4/4 cases<ref name=pmid19212771/>). | ||
**Endothelial cells +ve control. | **Endothelial cells +ve control. | ||
*S-100 +ve. | *S-100 +ve (4/4 cases<ref name=pmid19212771>{{Cite journal | last1 = Ertan | first1 = Y. | last2 = Sezak | first2 = M. | last3 = Turhan | first3 = T. | last4 = Kantar | first4 = M. | last5 = Erşahin | first5 = Y. | last6 = Mutluer | first6 = S. | last7 = Vergin | first7 = C. | last8 = Oniz | first8 = H. | last9 = Akalin | first9 = T. | title = Atypical teratoid/rhabdoid tumor of the central nervous system: clinicopathologic and immunohistochemical features of four cases. | journal = Childs Nerv Syst | volume = 25 | issue = 6 | pages = 707-11 | month = Jun | year = 2009 | doi = 10.1007/s00381-009-0811-0 | PMID = 19212771 }}</ref>. | ||
**Few other brain tumours express it. | **Few other brain tumours express it. | ||
*Vimentin +ve | *Vimentin +ve - perinuclear condensation (4/4 cases<ref name=pmid19212771/>). | ||
Others: | Others: | ||
*GFAP +ve (focal - in tumour cells). | *GFAP +ve (focal - in tumour cells). | ||
*EMA +ve | *EMA +ve - patchy cytoplasmic (4/4 cases<ref name=pmid19212771/>). | ||
*Smooth muscle actin +ve. | *Smooth muscle actin +ve.(4/4 cases<ref name=pmid19212771/>). | ||
*Cytokeratin +ve.{{fact}} | |||
==See also== | ==See also== | ||