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→Pathologic: +description of CBN
(→Tamponade: wikify) |
(→Pathologic: +description of CBN) |
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*10-21 days - Fibrovascular response, prominent granulation tissue. | *10-21 days - Fibrovascular response, prominent granulation tissue. | ||
*6 weeks - Fibrosis. | *6 weeks - Fibrosis. | ||
=====Contraction band necrosis===== | |||
General: | |||
*Mediated by catecholamines.<ref>{{cite journal |author=Hopster DJ, Milroy CM, Burns J, Roberts NB |title=Necropsy study of the association between sudden cardiac death, cardiac isoenzymes and contraction band necrosis |journal=J. Clin. Pathol. |volume=49 |issue=5 |pages=403–6 |year=1996 |month=May |pmid=8707956 |pmc=500481 |doi= |url=}}</ref> | |||
*Thought to arise in reperfusion from hypercontraction. | |||
Microscopic: | |||
*Thick intensely eosinophilic staining bands (on H&E) ~ typically 4-5 micrometres wide | |||
**Span the short axis of myocyte. | |||
**Can be thought of bunched-up striae. | |||
Notes: | |||
*Better seen with special stains (Masson or Gomori trichrome).<ref>{{cite journal |author=Hopster DJ, Milroy CM, Burns J, Roberts NB |title=Necropsy study of the association between sudden cardiac death, cardiac isoenzymes and contraction band necrosis |journal=J. Clin. Pathol. |volume=49 |issue=5 |pages=403–6 |year=1996 |month=May |pmid=8707956 |pmc=500481 |doi= |url=}}</ref> | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:MI_with_contraction_bands_high_mag.jpg CBN - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:MI_with_contraction_bands_very_high_mag.jpg CBN - very high mag. (WC)]. | |||
====Gross==== | ====Gross==== | ||