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Difference between revisions of "Extramammary Paget disease"
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Extramammary Paget disease (view source)
Revision as of 16:14, 6 February 2014
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Extramammary_Paget_disease_-_high_mag.jpg | |||
| Width = | |||
| Caption = Extramammary Paget's disease. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = large epithelioid cells - nested or single - in the epidermis, clear/pale cytoplasm (occasionally eosinophilic), large nucleoli | |||
| Subtypes = | |||
| LMDDx = benign Toker cell hyperplasia, [[malignant melanoma]], [[Bowen's disease]], [[apocrine carcinoma of the skin]] | |||
| Stains = | |||
| IHC = CK7 +ve, CEA +ve, S-100 -ve, CK5/6 -ve, HER2 +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = erythema, +/-weeping, +/-crusted | |||
| Grossing = | |||
| Site = [[vulva]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = pruritis (itchy) | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = typically benign - usually ''not'' associated with an underlying malignancy (unlike [[Paget's diseae of the breast]]) | |||
| Other = | |||
| ClinDDx = [[contact dermatitis]], [[lichen sclerosus]] | |||
| Tx = | |||
}} | |||
'''Extramammary Paget disease''', abbreviated '''EMPD''', is a skin disease. As the name suggests, there is also a [[Paget disease of the breast]]. | '''Extramammary Paget disease''', abbreviated '''EMPD''', is a skin disease. As the name suggests, there is also a [[Paget disease of the breast]]. | ||