Difference between revisions of "Case 30"

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51 bytes added ,  22:42, 14 March 2014
 
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===Provided clinical history===
===Provided clinical history===
30 year old woman, nephrotic syndrome
30 year old woman, anasarca and renal failure


===Site===
===Site===
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[[Image: Membranous_nephropathy_-_mpas_-_high_mag.jpg |500px|link=|center|]]
[[Image: Membranous_nephropathy_-_mpas_-_high_mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>
<center>High magnification. [[Jones stain]].</center>


{{hidden|Very high magnification|[[Image: Membranous nephropathy - cropped - mpas - very high mag.jpg |500px|link=|center|]]
{{hidden|Very high magnification|[[Image: Membranous nephropathy - cropped - mpas - very high mag.jpg |500px|link=|center|]]
<center>Very high magnification. [[H&E stain]].</center>}}
<center>Very high magnification. [[Jones stain]].</center>}}
 
===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}


===Additional tests===
===Additional tests===
====More history====
====More history====
{{hidden|More history|<center>ANA normal, Anti-Sm normal, Anti-dsDNA normal, HBV core -ve, HBV surf +ve, HCV -ve, No history of cancer.</center>}}
{{hidden|More history|<center>Proteinuria (4 g/24h), hypercholesterolemia, hypoalbuminemia, ANA -ve, Anti-Sm -ve, Anti-dsDNA -ve, HBV core -ve, HBV surf +ve, HCV -ve, no history of cancer.</center>}}


====Ask a colleague====
====Immunofluorescence====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}
{{hidden|IF|<center>Diffuse granular capillary loop - IgG, C3, kappa, lambda.</center>}}
 
====Electron microscopy====
{{hidden|EM|<center>Diffuse subepithelial deposits - spike forming.</center>}}


====Stains====
====Stains====
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| warthinstarry=  
| warthinstarry=  
}}
}}
====IHC====
====IHC====
{{Case IHC
{{Case IHC
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}}
}}


====Chromosomal translocations====
====Ask a colleague====
{{Case Translocations
{{hidden|Ask a colleague|<center>It is a [[nephrotic syndrome]]. It doesn't look like [[FSGS]] or [[minimal change disease]]... so, it's what is left.</center>}}
| blank=Dr Torres would ask why!
 
| t1_13=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t2_13=
| t21_22=
| t8_14=
| t9_22=
| t9_22=
| tx_17=
| tx_18=
}}
===Diagnosis===
===Diagnosis===
{{hidden|Diagnosis|<center>[[Membranous nephropathy]]</center>}}
{{hidden|Diagnosis|<center>[[Membranous nephropathy]] - probably idiopathic</center>}}
<br>
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===Other cases===
===Other cases===
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[[Category:Cases in medical kidney pathology]]
[[Category:Cases in medical kidney pathology]]
[[Category:Cases difficulty 5]]
[[Category:Cases difficulty 5]]
[[Category:Cases in medical kidney pathology - senior]]
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