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| ==Hemangioblastoma== | | ==Hemangioblastoma== |
| ===General===
| | {{Main|Hemangioblastoma}} |
| *Usually ''cerebellar''.
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| *Associated with [[von Hippel-Lindau syndrome]].
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| *WHO grade I.<ref>URL: [http://www.expertconsultbook.com/expertconsult/ob/book.do?method=display&type=bookPage&decorator=none&eid=4-u1.0-B978-1-4160-4580-9..00019-8--sc0155&isbn=978-1-4160-4580-9 http://www.expertconsultbook.com/expertconsult/ob/book.do?method=display&type=bookPage&decorator=none&eid=4-u1.0-B978-1-4160-4580-9..00019-8--sc0155&isbn=978-1-4160-4580-9]. Accessed on: 9 December 2010.</ref>
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| ===Microscopic===
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| Features:<ref>URL: [http://emedicine.medscape.com/article/340994-media http://emedicine.medscape.com/article/340994-media]. Accessed on: 23 June 2010.</ref>
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| *Vascular.
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| *Polygonal stromal cells with:
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| **Hyperchromatic nuclei.
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| **Vacuolar cytoplasm.
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| DDx:
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| *Metastatic [[clear cell renal cell carcinoma]].
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| ====Images====
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| <gallery>
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| Image:Cerebellar_hemangioblastoma_intermed_mag.jpg | Hemangioblastoma - intermed. mag. (WC)
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| Image:Cerebellar_hemangioblastoma_high_mag.jpg | Hemangioblastoma - high mag. (WC)
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| Image:Hemangioblastoma_-_nse_-_intermed_mag.jpg | Hemangioblastoma - NSE - intermed. mag. (WC)
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| </gallery>
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| www:
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| *[http://path.upmc.edu/cases/case342.html Hemangioblastoma - several images (upmc.edu)].
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| ===IHC===
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| Features:<ref>URL: [http://www.nature.com/modpathol/journal/v18/n6/full/3800351a.html http://www.nature.com/modpathol/journal/v18/n6/full/3800351a.html]. Accessed on: 9 December 2010.</ref>
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| *Alpha-inhibin +ve (cytoplasm).
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| *EMA -ve.
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| **RCC typically +ve.
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| *NSE +ve (nucleus + cytoplasm).
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| **RCC typically -ve.
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| ==Medulloblastoma== | | ==Medulloblastoma== |