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Difference between revisions of "Spitz nevus"
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'''Spitz nevus''', also known as ''epithelioid and spindle-cell nevus''', is an uncommon [[melanocytic lesion]] that can be difficult to differentiate from [[malignant melanoma]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Spitz_nevus_-_high_mag.jpg | |||
| Width = | |||
| Caption = Spitz nevus. [[H&E stain]]. | |||
| Micro = nests of cells (spindle, epithelioid or spindle/epithelioid) - in both dermis and epidermis - nests are vertically arranged ("hanging bananas"), +/-hyperkeratosis, +/-hypergranulosis, +/-[[acanthosis]] (thick stratum spinosum), Kamino bodies - dense eosinophilic bodies (rare in melanoma) | |||
| Subtypes = | |||
| LMDDx = [[malignant melanoma]], [[pigmented spindle cell nevus of Reed]] | |||
| Stains = HMB-45 -ve deep aspect, Ki-67 usu. low | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[skin]] - typically face or extremity | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = children and adolescents | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[melanoma]], other [[melanocytic lesions]] | |||
}} | |||
'''Spitz nevus''', also known as '''epithelioid and spindle-cell nevus''', is an uncommon [[melanocytic lesion]] that can be difficult to differentiate from [[malignant melanoma]]. | |||
==General== | ==General== | ||