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Difference between revisions of "Neuropathology tumours"
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→Astrocytomas: re-arr., subdivide
(+CPA tumours) |
(→Astrocytomas: re-arr., subdivide) |
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*Glial processes - '''key feature'''. | *Glial processes - '''key feature'''. | ||
**Thin stringy cytoplasmic processes - best seen at high power in less cellular areas. | **Thin stringy cytoplasmic processes - best seen at high power in less cellular areas. | ||
Images: | |||
*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/N0A002-PQ01-M.htm Endothelial proliferation in a GBM (ouhsc.edu)]. | *[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/N0A002-PQ01-M.htm Endothelial proliferation in a GBM (ouhsc.edu)]. | ||
*[http://moon.ouhsc.edu/kfung/jty1/neurotest/Q05-Ans.htm Endothelial proliferation (ouhse.edu)]. | *[http://moon.ouhsc.edu/kfung/jty1/neurotest/Q05-Ans.htm Endothelial proliferation (ouhse.edu)]. | ||
| Line 86: | Line 82: | ||
**Glial: "blends into brain"/gradual transition to non-tumour brain. | **Glial: "blends into brain"/gradual transition to non-tumour brain. | ||
**Non-glial: no glial processes. | **Non-glial: no glial processes. | ||
====Grading==== | |||
At least grade II: | |||
*Nuclear pleomorphism. | |||
At least grade III: | |||
*Mitotic figures. | |||
At least grade IV: | |||
*Microvascular proliferation ''or'' necrosis with pseudopalisading tumour cells. | |||
**Pseudopalisading tumour cells = high tumour cell density adjacent to regions of necrosis; palisade = a fence of pales forming a defense barrier or fortification. | |||
==Pilocytic astrocytoma== | ==Pilocytic astrocytoma== | ||