Difference between revisions of "Neuropathology tumours"

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→‎Meningioma: fix classification
(→‎Meningioma: fix classification)
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**Low mitotic rate.
**Low mitotic rate.
*Grade 2:  
*Grade 2:  
**Intermediate mitotic rate (>= 4 mitoses/HPF - for whatever ''HPF'' means, see [[HPFitis]].)
**Brain-invasive meningioma.
**Three of the following five features:
***Protrusion of meningioma into brain.
**#Sheeting architecture.
****Meninogioma with entraped GFAP +ve tissue.
**#High NC ratio; clusters of "lymphocyte-like" cells.
**Atypical meningioma.
**#Hypercellularity.
***Intermediate mitotic rate (>= 4 mitoses/10 HPF - for whatever ''HPF'' means, see [[HPFitis]].)
**#Macronucleoli.
***Three of the following five features:
**#Necrosis not caused by treatment, e.g. radiation or embolization.
***#Sheeting architecture.
***#High NC ratio; clusters of "lymphocyte-like" cells.
***#Hypercellularity.
***#Macronucleoli.
***#Necrosis not caused by treatment, e.g. radiation or embolization.
*Grade 3:
*Grade 3:
**High mitotic rate (>=20 mitoses/HPF - for whatever ''HPF'' means, see [[HPFitis]].)
**High mitotic rate (>=20 mitoses/10 HPF - for whatever ''HPF'' means, see [[HPFitis]].)
**"Frank anaplasia"; marked nuclear atypia.
**"Frank anaplasia"; marked nuclear atypia.


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