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Difference between revisions of "Inflammatory bowel disease"
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Inflammatory bowel disease (view source)
Revision as of 13:22, 19 October 2013
, 13:22, 19 October 2013→Crohn's disease vs. ulcerative colitis
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==Crohn's disease | ==Crohn's disease versus ulcerative colitis== | ||
*Some cases cannot be classified by the experts (see [[Inflammatory_bowel_disease#.22Indeterminate_colitis.22|"indeterminate colitis"]]). | *Some cases cannot be classified by the experts (see [[Inflammatory_bowel_disease#.22Indeterminate_colitis.22|"indeterminate colitis"]]). | ||
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** UC may have 'ileal backwash' -- mild ileal inflammation due to backwash of inflammatory soup from colon. | ** UC may have 'ileal backwash' -- mild ileal inflammation due to backwash of inflammatory soup from colon. | ||
*"No granulomas". | *"No granulomas". | ||
**Superficial [[granulomas]] in the mucosa are non-specific, especially if they are beside an | **Superficial [[granulomas]] in the mucosa are non-specific, especially if they are beside an inflamed crypt, i.e. they may be present in UC.<ref name=pmid12147095>{{Cite journal | last1 = Shepherd | first1 = NA. | title = Granulomas in the diagnosis of intestinal Crohn's disease: a myth exploded? | journal = Histopathology | volume = 41 | issue = 2 | pages = 166-8 | month = Aug | year = 2002 | doi = | PMID = 12147095 }}</ref><ref name=pmid12121237>{{Cite journal | last1 = Mahadeva | first1 = U. | last2 = Martin | first2 = JP. | last3 = Patel | first3 = NK. | last4 = Price | first4 = AB. | title = Granulomatous ulcerative colitis: a re-appraisal of the mucosal granuloma in the distinction of Crohn's disease from ulcerative colitis. | journal = Histopathology | volume = 41 | issue = 1 | pages = 50-5 | month = Jul | year = 2002 | doi = | PMID = 12121237 }}</ref> | ||
***Deep granulomas are specific for Crohn's disease. | ***Deep granulomas are specific for Crohn's disease. | ||