Difference between revisions of "Non-malignant skin disease"

Non-malignant skin disease (view source)

1,327 bytes removed , 18:01, 3 August 2013

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 ==Cicatrix==
-*[[AKA]] ''scar'', ''dermal scar''.
+{{Main|Dermal scar]]
-===General===
-*Previous surgery, biopsy, trauma.
-===Microscopic===
-Features:
-*Loss of dermal papilla.
-*Dense collagen - fibers run parallel to the dermal-epidermal (DE) junction<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - '''key feature'''.
-*Loss of adnexal structures.
-Other feature:
-*Thin-walled blood vessels.
-**Described as running perpendicular to the surface<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - this may not be apparent.
-Note:
-*There should not be any nuclear hyperchromasia or pleomorphism.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref>
-DDx:
-*[[Malignant melanoma]], desmoplastic-neurotropic type - nuclear pleomorphism and/or hyperchromasia; may be focal.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref>
-*[[Dermatofibroma]].
-*Desmoplastic [[Spitz nevus]].
-*Sclerosing [[blue nevus]].
-Image:
-*[http://commons.wikimedia.org/wiki/File:ScarHistology.JPG Scar (WC)].
-===IHC===
-*S100 focal/scattered +ve.
-**Desmoplastic melanoma strong +ve.
-*HMB-45 -ve.
-**Sclerosing blue nevus +ve.
-===Sign out===
-<pre>
-SKIN, LOWER MID BACK, RE-EXCISION:
-- DERMAL SCAR.
-- SOLAR ELASTOSIS.
-</pre>
-====Micro====
-The sections show skin with a dermis with dense collagen fibres that run parallel to the skin surface without adnexal structures.  The overlying dermal-epidermis interface lacks the typical undulation.
 ==Fibroepithelial polyp==