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Difference between revisions of "Neuropathology tumours"
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→Astrocytomas
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==Astrocytomas== | ==Astrocytomas== | ||
===Overview=== | |||
*Pilocytic astrocytomas (WHO Grade I). | *Pilocytic astrocytomas (WHO Grade I). | ||
*Dysembryoplastic neuroepithelial tumour (DNT), (WHO Grade I). | *Dysembryoplastic neuroepithelial tumour (DNT), (WHO Grade I). | ||
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*Glioblastoma (Grade IV). | *Glioblastoma (Grade IV). | ||
===Microscopic=== | |||
Features:<ref name=pmid>{{cite journal |author=Rong Y, Durden DL, Van Meir EG, Brat DJ |title='Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis |journal=J. Neuropathol. Exp. Neurol. |volume=65 |issue=6 |pages=529–39 |year=2006 |month=June |pmid=16783163 |doi= |url=}}</ref><ref>[http://dictionary.reference.com/browse/palisading http://dictionary.reference.com/browse/palisading]</ref> | Features:<ref name=pmid>{{cite journal |author=Rong Y, Durden DL, Van Meir EG, Brat DJ |title='Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis |journal=J. Neuropathol. Exp. Neurol. |volume=65 |issue=6 |pages=529–39 |year=2006 |month=June |pmid=16783163 |doi= |url=}}</ref><ref>[http://dictionary.reference.com/browse/palisading http://dictionary.reference.com/browse/palisading]</ref> | ||
*Nuclear pleomorphism. | *Nuclear pleomorphism. | ||
*Mitotic figures. | *Mitotic figures. | ||
*Microvascular proliferation or necrosis with pseudopalisading tumour cells. | *Microvascular proliferation ''or'' necrosis with pseudopalisading tumour cells. | ||
**Pseudopalisading tumour cells = high tumour cell density adjacent to regions of necrosis; palisade = a fence of pales forming a defense barrier or fortification. | **Pseudopalisading tumour cells = high tumour cell density adjacent to regions of necrosis; palisade = a fence of pales forming a defense barrier or fortification. | ||
Image: | |||
*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/N0A002-PQ01-M.htm Endothelial proliferation in a GBM (ouhsc.edu)]. | |||
==Filum terminale== | ==Filum terminale== | ||