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Difference between revisions of "Glioblastoma"
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| ClinDDx = [[metastatic]] carcinoma | | ClinDDx = [[metastatic]] carcinoma | ||
}} | }} | ||
'''Glioblastoma''' a very common malignant [[brain tumour]] in adults. | '''Glioblastoma''' a very common malignant primary [[brain tumour]] in adults. It has a very poor prognosis. | ||
It was previously known as ''glioblastoma multiforme'', abbreviated ''GBM''. | It was previously known as ''glioblastoma multiforme'', abbreviated ''GBM''. | ||
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**Nuclear atypia. | **Nuclear atypia. | ||
**Necrosis. | **Necrosis. | ||
**Endothelial proliferation (AKA microvascular proliferation). | **Endothelial proliferation ([[AKA]] microvascular proliferation). | ||
**+/-"Pseudopalisading necrosis" - tumour cells lined-up like a picket fence around necrotic areas. | **+/-"Pseudopalisading necrosis" - tumour cells lined-up like a picket fence around necrotic areas. | ||