Difference between revisions of "Thromboangiitis obliterans"

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*Stop smoking.<ref name=pmid22284771>{{Cite journal  | last1 = Dargon | first1 = PT. | last2 = Landry | first2 = GJ. | title = Buerger's disease. | journal = Ann Vasc Surg | volume = 26 | issue = 6 | pages = 871-80 | month = Aug | year = 2012 | doi = 10.1016/j.avsg.2011.11.005 | PMID = 22284771 }}</ref>
*Stop smoking.<ref name=pmid22284771>{{Cite journal  | last1 = Dargon | first1 = PT. | last2 = Landry | first2 = GJ. | title = Buerger's disease. | journal = Ann Vasc Surg | volume = 26 | issue = 6 | pages = 871-80 | month = Aug | year = 2012 | doi = 10.1016/j.avsg.2011.11.005 | PMID = 22284771 }}</ref>


===Formal criteria===
===Formal clinical criteria===
All of the following:<ref name=pmid16722538>{{Cite journal  | last1 = Arkkila | first1 = PE. | title = Thromboangiitis obliterans (Buerger's disease). | journal = Orphanet J Rare Dis | volume = 1 | issue = | pages = 14 | month = | year = 2006 | doi = 10.1186/1750-1172-1-14 | PMID = 16722538 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523324/ | PMC = 1523324 }}</ref><ref name=pmid10995867>{{Cite journal  | last1 = Olin | first1 = JW. | title = Thromboangiitis obliterans (Buerger's disease). | journal = N Engl J Med | volume = 343 | issue = 12 | pages = 864-9 | month = Sep | year = 2000 | doi = 10.1056/NEJM200009213431207 | PMID = 10995867 | URL = http://www.nejm.org/doi/full/10.1056/NEJM200009213431207 }}</ref>
All of the following - as per ''Olin'':<ref name=pmid10995867>{{Cite journal  | last1 = Olin | first1 = JW. | title = Thromboangiitis obliterans (Buerger's disease). | journal = N Engl J Med | volume = 343 | issue = 12 | pages = 864-9 | month = Sep | year = 2000 | doi = 10.1056/NEJM200009213431207 | PMID = 10995867 | URL = http://www.nejm.org/doi/full/10.1056/NEJM200009213431207 }}</ref><ref name=pmid16722538>{{Cite journal  | last1 = Arkkila | first1 = PE. | title = Thromboangiitis obliterans (Buerger's disease). | journal = Orphanet J Rare Dis | volume = 1 | issue = | pages = 14 | month = | year = 2006 | doi = 10.1186/1750-1172-1-14 | PMID = 16722538 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523324/ | PMC = 1523324 }}</ref>
*Less than 45 years old.
*Less than 45 years old.
*Current or recent tobacco use.
*Current or recent tobacco use.
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** Endarteritis - neutrophils at the internal elastic lamina (IEL).  
** Endarteritis - neutrophils at the internal elastic lamina (IEL).  
** Periarteritis - neutrophils around the arteries.
** Periarteritis - neutrophils around the arteries.
*Obliteration of the lumen - intimal thickening.
*Obliteration of the lumen.
**Thrombi.
**Organizing thrombi - thickened tunica intima.


Notes:
Notes:
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