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Difference between revisions of "Neuropathology tumours"
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→Common neuropathology tumours in a table
(→Ganglioneuroma: +IHC) |
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| Line 101: | Line 101: | ||
|missed lesion? | |missed lesion? | ||
|nil | |nil | ||
|[ | |[[Image:Grey_matter_and_white_matter_-_very_high_mag.jpg |thumb|center|150px|Normal. (WC)]] | ||
|- | |- | ||
|[[Reactive astrocytes]] | |[[Reactive astrocytes]] | ||
| Line 109: | Line 109: | ||
|missed lesion / close to a lesion; non-specific pathologic process - need more tissue | |missed lesion / close to a lesion; non-specific pathologic process - need more tissue | ||
|nil | |nil | ||
|[ | |[[Image:Reactive_astrocytes_-_lfb_-_high_mag.jpg|thumb|center|150px|Reactive astrocytes. (WC)]] | ||
|- | |- | ||
|[[Astrocytoma]] (grade II or worse) | |[[Astrocytoma]] (grade II or worse) | ||
| Line 117: | Line 117: | ||
|very common, esp. glioblastoma | |very common, esp. glioblastoma | ||
|IDH-1+/-, GFAP+ | |IDH-1+/-, GFAP+ | ||
|[ | | [[Image:Anaplastic_astrocytoma_-_very_high_mag_-_cropped.jpg | thumb| center| 150px|Astrocytoma. (WC)]] | ||
|- | |- | ||
|[[Metastatic brain tumours|Metastasis]] | |[[Metastatic brain tumours|Metastasis]] | ||
| Line 125: | Line 125: | ||
|often suspected to have metastatic disease | |often suspected to have metastatic disease | ||
|TTF-1, CK7, CK20, BRST-2 | |TTF-1, CK7, CK20, BRST-2 | ||
|[ | |[[Image:Metastatic_adenocarcinoma_-_cerebellum_-_very_low_mag.jpg | thumb| center|150px |Metastasis. (WC)]] | ||
|- | |- | ||
|[[Meningioma]] | |[[Meningioma]] | ||
| Line 133: | Line 133: | ||
|may be diagnosed on smear, DDx: choroid plexus, schwannoma | |may be diagnosed on smear, DDx: choroid plexus, schwannoma | ||
|EMA, PR, Ki-67 | |EMA, PR, Ki-67 | ||
|[ | |[[Image:Meningioma_intermed_mag.jpg |thumb|center|150px|Meningioma. (WC)]] | ||
|- | |- | ||
|[[Schwannoma]] | |[[Schwannoma]] | ||
| Line 141: | Line 141: | ||
|need frozen section to Dx | |need frozen section to Dx | ||
|S100 | |S100 | ||
|[ | |[[Image:Schwannoma_-_Antoni_A_and_B_-_very_high_mag.jpg|thumb|center|150px|Schwannoma. (WC)]] | ||
[ | |||
|} | |} | ||
† Rosenthal fibres at the periphery of a lesion are a non-specific finding seen in chronic processes. | † Rosenthal fibres at the periphery of a lesion are a non-specific finding seen in chronic processes. | ||