Difference between revisions of "Gastrointestinal tract polyps"

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| may be syndromic, e.g. [[hyperplastic polyposis syndrome]]
| may be syndromic, e.g. [[hyperplastic polyposis syndrome]]
| [[sessile serrated adenoma]]
| [[sessile serrated adenoma]]
| [http://commons.wikimedia.org/wiki/File:Hyperplastic_polyp2.jpg HP (WC)]
| [[Image:Hyperplastic_polyp2.jpg|thumb|center|150px| HP (WC)]]
|-
|-
| [[Traditional adenoma]]
| [[Traditional adenoma]]
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| [[tubular adenoma of the gastrointestinal tract|tubular adenoma]], [[tubulovillous adenoma]], [[villous adenoma]]
| [[tubular adenoma of the gastrointestinal tract|tubular adenoma]], [[tubulovillous adenoma]], [[villous adenoma]]
| [[traditional serrated adenoma]], reactive changes (inflammation)
| [[traditional serrated adenoma]], reactive changes (inflammation)
| [http://commons.wikimedia.org/wiki/File:Tubular_adenoma_2_high_mag.jpg TA - high mag. (WC)], [http://commons.wikimedia.org/wiki/File:Tubular_adenoma_4_low_mag.jpg TA - low mag. (WC)]
| [[Image:Tubular_adenoma_4_low_mag.jpg|thumb|center|150px| TA (WC)]]
|}
|}


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| AKA sessile serrated polyp
| AKA sessile serrated polyp
| hyperplastic polyp
| hyperplastic polyp
| [http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma_2_low_mag.jpg SSA - low mag. (WC)]
| [[Image:Sessile_serrated_adenoma_2_low_mag.jpg|thumb|center|150px|SSA (WC)]]
|-
|-
| [[Traditional serrated adenoma]] (TSA)
| [[Traditional serrated adenoma]] (TSA)
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| called "traditional" to differentiate from SSA
| called "traditional" to differentiate from SSA
| traditional serrated adenoma (esp. villous adenoma)
| traditional serrated adenoma (esp. villous adenoma)
| [http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_low_mag.jpg TSA - low mag. (WC)], [http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_very_high_mag.jpg TSA - high mag. (WC)]  
| [[Image:Traditional_serrated_adenoma_low_mag.jpg|thumb|center|150px|TSA (WC)]]
|-
|-
| [[Juvenile polyp]] (retention polyp)
| [[Juvenile polyp]] (retention polyp)
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| may be part of [[juvenile polyposis syndrome]]
| may be part of [[juvenile polyposis syndrome]]
| inflammatory pseudopolyp
| inflammatory pseudopolyp
| [http://commons.wikimedia.org/wiki/File:Gastric_juvenile_polyp_-_very_low_mag.jpg Gastric JP - low mag. (WC)]
| [[Image:Gastric_juvenile_polyp_-_very_low_mag.jpg|thumb|center|150px|Gastric JP (WC)]]
|-
|-
| [[Inflammatory pseudopolyp]]
| [[Inflammatory pseudopolyp]]
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| PJP not pre-malignant lesion in itself; see ''[[Peutz-Jeghers syndrome]]''
| PJP not pre-malignant lesion in itself; see ''[[Peutz-Jeghers syndrome]]''
| normal, classically in the small bowel
| normal, classically in the small bowel
| [http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg PJP - low mag. (WC)]
| [[Image:Peutz-Jeghers_syndrome_polyp.jpg|thumb|center|150px|PJP (WC)]]
|}
|}


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|-
|-
|Image(s)
|Image(s)
| [http://commons.wikimedia.org/wiki/File:Hyperplastic_polyp2.jpg low mag.]
| [[Image:Hyperplastic_polyp2.jpg|thumb|center|150px|HP (WC)]]
| [http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma_2_low_mag.jpg low mag], [http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma.jpg low mag.]
| [[Image:Sessile_serrated_adenoma_2_low_mag.jpg|thumb|center|150px|SSA (WC)]]
| [http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_low_mag.jpg low mag], [http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_very_high_mag.jpg very high mag.]
| [[Image:Traditional_serrated_adenoma_low_mag.jpg|thumb|center|150px|TSA (WC)]]
|[http://commons.wikimedia.org/wiki/File:Tubular_adenoma_2_low_mag.jpg low mag.], [http://commons.wikimedia.org/wiki/File:Tubular_adenoma_2_high_mag.jpg high mag.]
|[[Image:Tubular_adenoma_2_low_mag.jpg|thumb|center|150px|TA (WC)]]
|}
|}
Normal colonic mucosa:  
Normal colonic mucosa:  
Line 240: Line 240:
*[[Collagenous colitis]].
*[[Collagenous colitis]].


Images:
====Images====
<gallery>
Image:Tubular_adenoma_2_intermed_mag.jpg| Normal colon adjacent to a tubular adenoma. (WC/Nephron)
</gallery>
www:
*[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/images/col10he.jpg Normal colorectal mucosa (uwa.edu.au)].<ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/git.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/git.htm]. Accessed on: 18 October 2012.</ref>
*[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/images/col10he.jpg Normal colorectal mucosa (uwa.edu.au)].<ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/git.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/GIT/git.htm]. Accessed on: 18 October 2012.</ref>
*[http://www.siumed.edu/~dking2/erg/GI027b.htm Colon (siumed.edu)].
*[http://www.siumed.edu/~dking2/erg/GI027b.htm Colon (siumed.edu)].
*[http://commons.wikimedia.org/wiki/File:Tubular_adenoma_2_intermed_mag.jpg Normal colon adjacent to a tubular adenoma (WC)].
*[http://www.gwc.maricopa.edu/class/bio202/Digestive/DigestHisto/ColonA.htm Normal colorectal mucosa (maricopa.edu)].
*[http://www.gwc.maricopa.edu/class/bio202/Digestive/DigestHisto/ColonA.htm Normal colorectal mucosa (maricopa.edu)].


Line 357: Line 360:
*[[Normal colon]].
*[[Normal colon]].


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Hyperplastic_polyp1.jpg HP - high mag. (WC)].
Image:Hyperplastic_polyp1.jpg | HP - high mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Hyperplastic_polyp2.jpg HP - lower mag. (WC)].
Image:Hyperplastic_polyp2.jpg | HP - lower mag. (WC/Nephron)
*www:
</gallery>
**[http://www.flickr.com/photos/jthetzel/4317282727/ Microvesicular HP (flickr.com/jhetzel)].  
www:
**[http://www.flickr.com/photos/jian-hua_qiao_md/3984355417/ HP of colon (flickr.com/jian-hua_qiao_md)].
*[http://www.flickr.com/photos/jthetzel/4317282727/ Microvesicular HP (flickr.com/jhetzel)].  
*[http://www.flickr.com/photos/jian-hua_qiao_md/3984355417/ HP of colon (flickr.com/jian-hua_qiao_md)].


====Subclassification====
====Subclassification====
Line 559: Line 563:
====Images====
====Images====
<gallery>
<gallery>
Image:Tubular_adenoma_high_mag.jpg| Small tubular adenoma - high mag. (WC/Nephron).
Image:Tubular_adenoma_4_low_mag.jpg| Small tubular adenoma - low mag. (WC/Nephron).
Image:Tubular_adenoma_4_high_mag.jpg| Small tubular adenoma - high mag. (WC/Nephron).
Image:Tubular_adenoma_2_intermed_mag.jpg| Tubular adenoma - intermed. mag. (WC/Nephron).
Image:Tubular_adenoma_2_intermed_mag.jpg| Tubular adenoma - intermed. mag. (WC/Nephron).
Image:Tubulovillous_adenoma.jpg| Tubulovillous adenoma (WC/Nephron).
Image:Tubulovillous_adenoma.jpg| Tubulovillous adenoma (WC/Nephron).
Line 729: Line 734:
*[[Villous adenoma]].
*[[Villous adenoma]].


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_low_mag.jpg TSA - low mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_intermed_mag.jpg TSA - intermed. mag. (WC)].
Image:Traditional_serrated_adenoma_low_mag.jpg | TSA - low mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Traditional_serrated_adenoma_very_high_mag.jpg TSA - very high mag. (WC)].
Image:Traditional_serrated_adenoma_intermed_mag.jpg | TSA - intermed. mag. (WC/Nephron)
 
Image:Traditional_serrated_adenoma_very_high_mag.jpg | TSA - very high mag. (WC/Nephron)
</gallery>
==Sessile serrated adenoma==
==Sessile serrated adenoma==
*Often abbreviated ''SSA''.
*Often abbreviated ''SSA''.
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*[[Tubular adenoma of the gastrointestinal tract|Tubular adenoma]] - for ''SSA with dysplasia'', TAs often less than 1 cm (uncommon for SSAs).
*[[Tubular adenoma of the gastrointestinal tract|Tubular adenoma]] - for ''SSA with dysplasia'', TAs often less than 1 cm (uncommon for SSAs).


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma.jpg SSA - low mag. (WC/Nephron)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma2.jpg SSA - intermed. mag. (WC/Nephron)].
Image:Sessile_serrated_adenoma.jpg | SSA - low mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma3.jpg SSA - high mag. (WC/Nephron)].
Image:Sessile_serrated_adenoma2.jpg | SSA - intermed. mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Sessile_serrated_adenoma_3_low_mag.jpg SSA - low mag. (WC/Nephron)].
Image:Sessile_serrated_adenoma3.jpg | SSA - high mag. (WC/Nephron)
 
Image:Sessile_serrated_adenoma_3_low_mag.jpg | SSA - low mag. (WC/Nephron)
</gallery>
===Sign out===
===Sign out===
<pre>
<pre>
Line 851: Line 858:
</ref>
</ref>


Image:
====Image====
*[http://commons.wikimedia.org/wiki/File:Cecal_adenocarcinoma.jpg Colorectal carcinoma (WC)].
<gallery>
 
Image:Cecal_adenocarcinoma.jpg | Colorectal carcinoma. (WC/Nephron)
</gallery>
===Sign out===
===Sign out===
<pre>
<pre>
Line 909: Line 917:
*[[Cronkhite-Canada syndrome]] - have changes in the surrounding mucosa, clinical findings (nail atrophy, skin pigment, alopecia).
*[[Cronkhite-Canada syndrome]] - have changes in the surrounding mucosa, clinical findings (nail atrophy, skin pigment, alopecia).


Images:  
====Images====
www:
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f4.html Juvenile polyp (nature.com)].
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f4.html Juvenile polyp (nature.com)].
*[http://commons.wikimedia.org/wiki/File:Gastric_juvenile_polyp_-_very_low_mag.jpg Juvenile polyp of the stomach - very low mag. (WC)]
<gallery>
*[http://commons.wikimedia.org/wiki/File:Gastric_juvenile_polyp_-_2_-_very_low_mag.jpg Juvenile polyp of the stomach - very low mag. (WC)].
Image:Gastric_juvenile_polyp_-_very_low_mag.jpg | Juvenile polyp of the stomach - very low mag. (WC/Nephron)
 
Image:Gastric_juvenile_polyp_-_2_-_very_low_mag.jpg | Juvenile polyp of the stomach - very low mag. (WC/Nephron)
</gallery>
===IHC===
===IHC===
*Usually none.
*Usually none.
Line 958: Line 968:
***"Thick" ~= thickness of muscularis mucosae.
***"Thick" ~= thickness of muscularis mucosae.


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg Peutz-Jeghers polyp - intestine (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Gastric_Peutz-Jeghers_polyp_-_very_low_mag.jpg Peutz-Jeghers polyp - stomach (WC)].
Image:Peutz-Jeghers_syndrome_polyp.jpg | Peutz-Jeghers polyp - intestine (WC/Nephron)
Image:Gastric_Peutz-Jeghers_polyp_-_very_low_mag.jpg | Peutz-Jeghers polyp - stomach (WC/Nephron)  
</gallery>
www:
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f3.html Peutz-Jeghers polyp (nature.com)].
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f3.html Peutz-Jeghers polyp (nature.com)].


Line 1,027: Line 1,040:
**Large cells with a round nucleus and a prominent nucleolus.
**Large cells with a round nucleus and a prominent nucleolus.


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Ganglioneuroma_-_intermed_mag.jpg Ganglioneuroma - intermed. mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Ganglioneuroma_-_high_mag.jpg Ganglioneuroma - high mag. (WC)].
Image:Ganglioneuroma_-_intermed_mag.jpg | Ganglioneuroma - intermed. mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Ganglioneuroma_-_very_high_mag.jpg Ganglioneuroma - very high mag. (WC)].
Image:Ganglioneuroma_-_high_mag.jpg | Ganglioneuroma - high mag. (WC/Nephron)
 
Image:Ganglioneuroma_-_very_high_mag.jpg | Ganglioneuroma - very high mag. (WC/Nephron)
</gallery>
==Inflammatory myoglandular polyp==
==Inflammatory myoglandular polyp==
===General===
===General===
48,868

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