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Difference between revisions of "Urothelium"
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→Urothelial carcinoma in situ
m (→Micro) |
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*p53 +ve. | *p53 +ve. | ||
*Ki-67 high. | *Ki-67 high. | ||
Benign urothelium vs. CIS:<ref name=pmid16932015>{{Cite journal | last1 = Yin | first1 = H. | last2 = He | first2 = Q. | last3 = Li | first3 = T. | last4 = Leong | first4 = AS. | title = Cytokeratin 20 and Ki-67 to distinguish carcinoma in situ from flat non-neoplastic urothelium. | journal = Appl Immunohistochem Mol Morphol | volume = 14 | issue = 3 | pages = 260-5 | month = Sep | year = 2006 | doi = | PMID = 16932015 }}</ref> | |||
*CK20 +ve in deep cells (23/26 cases). | |||
**Normal urothelium -- only the umbrella cells. | |||
*Ki-67 ~50% of cells - deep and superficial. | |||
**Normal ~10% of cells, confined to basal aspect. | |||
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