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Difference between revisions of "Ovarian tumours"
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→Mucinous adenocarcinoma of the ovary: re-work
(→Mucinous adenocarcinoma of the ovary: re-work) |
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| Line 522: | Line 522: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Tall [[columnar cell]]s in glands. | *Mucinous differentiation. | ||
** | **Tall [[columnar cell]]s in glands with apical mucin. | ||
** | ***May have an endocervical-like ''or'' intestinal-like appearance - see ''subtypes''. | ||
* | *Invasive morphology - one of the following: | ||
*+/-Nuclear atypia. | *#Back-to-back glands/confluent growth pattern. | ||
*No [[ | *#Desmoplastic stromal response. | ||
* | *#Cribriforming of glands. | ||
*Malignant characteristics: | |||
**+/-Nuclear atypia. | |||
**+/-Necrosis. | |||
**No cilia. | |||
DDx: | |||
*[[Mucinous borderline tumour of the ovary]]. | |||
*[[Metastatic]] [[mucinous carcinoma]]. | |||
====Subtypes==== | ====Subtypes==== | ||
| Line 536: | Line 544: | ||
#''Intestinal type''. | #''Intestinal type''. | ||
#*More likely to be malignant. | #*More likely to be malignant. | ||
#*[[Goblet cell]]s. | #*+/-[[Goblet cell]]s. | ||
#**One large clear apical vacuole. | #**One large clear apical vacuole. | ||
#*If it doesn't look like intestine to you... it probably isn't. | #*If it doesn't look like intestine to you... it probably isn't. | ||