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Difference between revisions of "Melanocytic lesions"
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*Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis. | *Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis. | ||
*Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section. | *Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section. | ||
*Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''. | *+/-Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''. | ||
DDx: | DDx: | ||
*[[Melanoma in situ]] - especially on sun damaged skin ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref> | *[[Melanoma in situ]] - especially on [[solar elastosis|sun damaged skin]] ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref><ref name=pmid10911797>{{Cite journal | last1 = Edwards | first1 = SL. | last2 = Blessing | first2 = K. | title = Problematic pigmented lesions: approach to diagnosis. | journal = J Clin Pathol | volume = 53 | issue = 6 | pages = 409-18 | month = Jun | year = 2000 | doi = | PMID = 10911797 }}</ref> | ||
*[[Malignant melanoma]] - especially on sun damaged skin ([[lentigo maligna melanoma]]). | *[[Malignant melanoma]] - especially on sun damaged skin ([[lentigo maligna melanoma]]). | ||
*[[Compound melanocytic nevus]]. | *[[Compound melanocytic nevus]]. | ||