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===Management=== | ===Management=== | ||
====Dirty first approximation==== | ====Dirty first approximation==== | ||
The management changes between Gleason 6, 7 | *The management changes between Gleason score 6, 7 and 8. | ||
* Gleason 6: | |||
* Gleason 7: do something - surgery ''or'' radiation therapy. | Typically, the implications are: | ||
* Gleason 8+: bad cancer - do something quickly! | * Gleason 6: observation ''or'' radioactive seeds; surgery if patient wants. | ||
* Gleason 7: do something -- surgery ''or'' radiation therapy. | |||
* Gleason 8+: bad cancer -- do something quickly! | |||
Bottom line: | Bottom line: | ||
Line 35: | Line 37: | ||
=====Active surveillance===== | =====Active surveillance===== | ||
The ''Klotz'' criteria for active surveillance:<ref name=pmid22314081/><ref>{{Cite journal | last1 = Klotz | first1 = L. | title = Active surveillance for prostate cancer: for whom? | journal = J Clin Oncol | volume = 23 | issue = 32 | pages = 8165-9 | month = Nov | year = 2005 | doi = 10.1200/JCO.2005.03.3134 | PMID = 16278468 }}</ref> | |||
*Gleason score 6 or less. | *Gleason score 6 or less. | ||
*All biopsies cores < 50% involvement. | *All biopsies cores < 50% involvement. |
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