Difference between revisions of "Ochronosis"

'''Ochronosis''' is a disease characterized by the accumulation of homogentisic acid. It is subclassified as ''endogenous'' and ''exogenous''.

The endogenous form is genetic and autosomal recessive.<ref name=pmid20055850>{{Cite journal  | last1 = Turgay | first1 = E. | last2 = Canat | first2 = D. | last3 = Gurel | first3 = MS. | last4 = Yuksel | first4 = T. | last5 = Baran | first5 = MF. | last6 = Demirkesen | first6 = C. | title = Endogenous ochronosis. | journal = Clin Exp Dermatol | volume = 34 | issue = 8 | pages = e865-8 | month = Dec | year = 2009 | doi = 10.1111/j.1365-2230.2009.03618.x | PMID = 20055850 }}</ref> '''Alcaptonuria''' is a specific genetic defect that causes ochronosis.<ref>{{OMIM|203500}}</ref>