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Difference between revisions of "Diffuse large B-cell lymphoma"
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Diffuse large B-cell lymphoma (view source)
Revision as of 17:23, 24 December 2012
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COMMENT: | COMMENT: | ||
The tumour consists of cells approximately 2x the size of mature lymphocytes. Mature lymphocytes are intermixed with the tumour. There is no gland formation. Follicle formation is not apparent. | The tumour consists of cells approximately 2x the size of mature | ||
lymphocytes. Mature lymphocytes are intermixed with the tumour. | |||
There is no gland formation. Follicle formation is not apparent. | |||
</pre> | |||
<pre> | |||
SPLEEN, SPLENECTOMY: | |||
- DIFFUSE LARGE B-CELL LYMPHOMA. | |||
COMMENT: | |||
Architecture: no gland formation, no follicle formation apparent, dyscohesive. | |||
Tumour cell size: 1.5-2x resting lymphocyte. | |||
Nucleoli: present. | |||
Cytoplasm: scant-to-moderate basophilic/grey. | |||
Proliferation: mitoses easily identified. | |||
Positive stains (tumour cells): | |||
CD45, CD20, BCL-2, BCL-6. | |||
Negative stains (tumour cells): | |||
pankeratin, S-100, MUM-1, CD3, CD5, CD10, CD21, CD30. | |||
Ki-67: 20% of cells. | |||
</pre> | </pre> | ||