Difference between revisions of "Peritoneum"

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Peritoneum (view source)

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→‎Peritoneal inclusion cyst
 
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:Should '''not''' be confused with ''[[malignant mesothelioma]]'' or ''[[benign multicystic mesothelioma]]''.
:Should '''not''' be confused with ''[[malignant mesothelioma]]'' or ''[[benign multicystic mesothelioma]]''.
*[[AKA]] ''benign papillary mesothelioma''.
*[[AKA]] ''benign papillary mesothelioma''.
===General===
{{Main|Well-differentiated papillary mesothelioma}}
*Benign.
*Classically women of reproductive age.<ref name=pmid18716115>{{Cite journal  | last1 = Park | first1 = JY. | last2 = Kim | first2 = KW. | last3 = Kwon | first3 = HJ. | last4 = Park | first4 = MS. | last5 = Kwon | first5 = GY. | last6 = Jun | first6 = SY. | last7 = Yu | first7 = ES. | title = Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis. | journal = AJR Am J Roentgenol | volume = 191 | issue = 3 | pages = 814-25 | month = Sep | year = 2008 | doi = 10.2214/AJR.07.3628 | PMID = 18716115 | URL = content/191/3/814.full.pdf}}</ref>
*Reported in tunica vaginalis of the [[testis]].<ref name=pmid1452778>{{Cite journal  | last1 = Chetty | first1 = R. | title = Well differentiated (benign) papillary mesothelioma of the tunica vaginalis. | journal = J Clin Pathol | volume = 45 | issue = 11 | pages = 1029-30 | month = Nov | year = 1992 | doi =  | PMID = 1452778 }}</ref>
 
===Gross===
Features - typical:
*Multiple peritoneal nodules.
*Ascites.
 
DDx:<ref name=pmid18716115/>
*[[Tuberculosis]].
*Carcinomatosis.
*[[Primary peritoneal serous carcinoma]].


===Microscopic===
==Peritoneal inclusion cyst==
Features:
{{Main|Peritoneal inclusion cyst}}
*Papillary structures with:
**Thick fibrous cores.
**Simple cuboidal epithelium.
***Small nucleoli.
 
Note:
*Lack cytologic atypia.
 
Image:
*[http://www.webpathology.com/image.asp?n=10&Case=86 Benign papillary mesothelioma (webpathology.com)].
 
==Benign multicystic mesothelioma==
:Should '''not''' be confused with ''[[malignant mesothelioma]]'' and ''[[benign papillary mesothelioma]]''.
*[[AKA]] ''peritoneal inclusion cyst''.<ref name=pmid19386139>{{Cite journal  | last1 = Vallerie | first1 = AM. | last2 = Lerner | first2 = JP. | last3 = Wright | first3 = JD. | last4 = Baxi | first4 = LV. | title = Peritoneal inclusion cysts: a review. | journal = Obstet Gynecol Surv | volume = 64 | issue = 5 | pages = 321-34 | month = May | year = 2009 | doi = 10.1097/OGX.0b013e31819f93d4 | PMID = 19386139 }}</ref>
*[[AKA]] ''inflammatory cyst of the peritoneum''.
*[[AKA]] ''inflammatory cyst of the peritoneum''.
*[[AKA]] ''[[mesothelial inclusion cyst]]''. (???)
*[[AKA]] ''[[mesothelial inclusion cyst]]''.{{fact}}
===General===
*[[AKA]] ''benign multicystic mesothelioma''.<ref name=pmid19386139>{{Cite journal  | last1 = Vallerie | first1 = AM. | last2 = Lerner | first2 = JP. | last3 = Wright | first3 = JD. | last4 = Baxi | first4 = LV. | title = Peritoneal inclusion cysts: a review. | journal = Obstet Gynecol Surv | volume = 64 | issue = 5 | pages = 321-34 | month = May | year = 2009 | doi = 10.1097/OGX.0b013e31819f93d4 | PMID = 19386139 }}</ref>
*Usually conservative management.
**Should '''not''' be confused with ''[[malignant mesothelioma]]'' and ''[[benign papillary mesothelioma]]''.
*Serum CA-125 usually low.
*May occur in men.<ref name=pmid12239771>{{Cite journal  | last1 = Cavallaro | first1 = A. | last2 = Murazio | first2 = M. | last3 = Modugno | first3 = P. | last4 = Vona | first4 = A. | last5 = Revelli | first5 = L. | last6 = Potenza | first6 = AE. | last7 = Colli | first7 = R. | title = Benign multicystic mesothelioma of the peritoneum: a case report. | journal = Chir Ital | volume = 54 | issue = 4 | pages = 569-72 | month =  | year =  | doi =  | PMID = 12239771 }}</ref>
 
===Gross===
Features:<ref name=pmid3789251>{{Cite journal  | last1 = McFadden | first1 = DE. | last2 = Clement | first2 = PB. | title = Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases. | journal = Am J Surg Pathol | volume = 10 | issue = 12 | pages = 844-54 | month = Dec | year = 1986 | doi =  | PMID = 3789251 }}</ref>
*Multilocular thin-walled cysts containing serous fluid +/- blood.
**Occasionally unilocular.
*May be up to 15 cm.
*Can be adherent to the [[ovary]].
 
===Microscopic===
Features:<ref name=pmid19386139/><ref name=pmid18349460>{{Cite journal  | last1 = Levy | first1 = AD. | last2 = Arnáiz | first2 = J. | last3 = Shaw | first3 = JC. | last4 = Sobin | first4 = LH. | title = From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. | journal = Radiographics | volume = 28 | issue = 2 | pages = 583-607; quiz 621-2 | month = | year = | doi = 10.1148/rg.282075175 | PMID = 18349460 | URL = http://radiographics.rsna.org/content/28/2/583.full}}</ref>
*Thin-walled, irregular-shaped, cysts - unicystic or multicystic.
**Mesothelial lining.
**Eosinophilic fluid.
 
DDx:
*[[Ovarian serous borderline tumour]].
 
Images:
*[http://radiographics.rsna.org/content/28/2/583/F30.expansion.html Multicystic mesothelioma (rsna.org)].
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445851/figure/F4/ Benign multicystic peritoneal mesothelioma (nih.gov)].<ref name=pmid22583977>{{Cite journal  | last1 = Takemoto | first1 = S. | last2 = Kawano | first2 = R. | last3 = Honda | first3 = K. | last4 = Nakazono | first4 = A. | last5 = Shimamatsu | first5 = K. | title = Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report. | journal = J Med Case Rep | volume = 6 | issue = 1 | pages = 126 | month =  | year = 2012 | doi = 10.1186/1752-1947-6-126 | PMID = 22583977 }}</ref>
 
===IHC===
Features:<ref name=pmid22583977/>
*Calretinin +ve.
*WT-1 +ve.
*D2-40 -ve. (???)


=Malignant=
=Malignant=
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===IHC===
===IHC===
*Like serous carcinoma elsewhere - see ''[[ovarian serous carcinoma]]''.
*Like serous carcinoma elsewhere - see ''[[ovarian serous carcinoma]]''.
===Sign out===
Should have comment something like:
<pre>
High-grade serous carcinoma of the ovary/fallopian tube/periteonum is associated
with BRCA1/2 mutation in approximately 20% of patients. Referral to genetic
counseling is recommended.
</pre>


==Malignant mesothelioma==
==Malignant mesothelioma==
{{Main|Malignant mesothelioma}}
{{Main|Malignant mesothelioma}}
This is like the tumour found in the pleural cavity.
This is like the tumour found in the pleural cavity.
==Peritoneal metastasis==
*[[AKA]] ''metastatic peritoneal disease''.
{{Main|Metastasis}}
===General===
Common causes:
*Gastrointestinal tract, esp. [[colorectal carcinoma]].
*Gynecologic tract.
Note:
*Peritoneal disease in the context of liver metastases in [[colorectal carcinoma]] contraindicates liver resection.<ref>{{Cite journal  | last1 = Elias | first1 = D. | last2 = Rougier | first2 = P. | last3 = Mankarios | first3 = H. | last4 = Fahrat | first4 = F. | last5 = Lasser | first5 = P. | title = [Resectable liver metastases and synchronous extra-hepatic sites of colorectal origin. Surgical indications]. | journal = Presse Med | volume = 22 | issue = 11 | pages = 515-20 | month = Mar | year = 1993 | doi =  | PMID = 8511077 }}</ref>
===Microscopic===
:See ''[[metastasis]]''.


=See also=
=See also=
Michael
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