Difference between revisions of "Non-malignant skin disease"

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*Microorganisms - '''key feature'''.
*Microorganisms - '''key feature'''.
**Often hyphae (candida) - like twigs of a tree... branching.
**Often hyphae (candida) - like twigs of a tree... branching.
*Perivascular inflammation.
***May be very fragmented in section ~ size of a neutrophil.
*Perivascular inflammation, esp. neutrophils.
*Exocytosis - blood cell infiltrate the epidermis.
*Exocytosis - blood cell infiltrate the epidermis.


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===Stains===
===Stains===
*[[GMS]].
*[[GMS stain]].
*[[PAS]].
*[[PAS-D stain]].
 
===Sign out===
<pre>
SKIN, BIOPSY:
- SKIN WITH SUPERFICIAL FUNGAL ORGANISMS CONSISTENT WITH CANDIDA.
- REACTIVE CHANGES OF THE EPITHELIUM.
</pre>
 
====Micro====
The sections show skin with a neutrophilic infiltrate in the superficial epidermis.  PAS-D staining demonstrates fungal organisms with a morphology suggestive of candida.
 
The epithelium has parakeratosis, acanthosis and spongiosis.  No mitotic activity is appreciated.  The keratinocytes are moderately enlarged and have evident nucleoli.


==Cicatrix==
==Cicatrix==
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