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Melanocytic lesions (view source)
Revision as of 01:23, 14 September 2012
, 01:23, 14 September 2012→Neurocristic hamartoma: +desmoplastic
(→Neurocristic hamartoma: +desmoplastic) |
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==Neurocristic hamartoma== | ==Neurocristic hamartoma== | ||
{{Main|Neurocristic hamartoma}} | {{Main|Neurocristic hamartoma}} | ||
==Desmoplastic melanocytic nevus== | |||
*[[AKA]] ''sclerosing melanocytic nevus''. | |||
===General=== | |||
*Benign. | |||
===Gross=== | |||
*Usu. "small" and symmetric. | |||
Clinical DDx: | |||
*[[Dermatofibroma]]. | |||
*[[Dermal scar]]. | |||
===Microscopic=== | |||
Features:<ref name=Ref_Derm_464>{{Ref Derm|464}}</ref> | |||
*[[Compound nevus]] ''or'' [[intradermal nevus]] with prominent dermal fibrosis. | |||
**Fibrosis: extra pink - versus surrounding. | |||
DDx: | |||
*[[Desmoplastic neurotropic malignant melanoma]]. | |||
*[[Dermatofibroma]]. | |||
===IHC=== | |||
Features:<ref name=Ref_Derm_464>{{Ref Derm|464}}</ref> | |||
*Melan A (MART-1) +ve (not usu. +ve in desmoplastic melanoma).<ref name=Ref_Derm_464>{{Ref Derm|464}}</ref> | |||
*S-100 +ve. | |||
*Ki-67 -- only rare cells. | |||
==See also== | ==See also== | ||