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Difference between revisions of "An introduction to head and neck pathology"
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An introduction to head and neck pathology (view source)
Revision as of 17:40, 1 May 2012
, 17:40, 1 May 2012→Branchial cleft cyst: tweak
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==Branchial cleft cyst== | ==Branchial cleft cyst== | ||
*[[AKA]] branchial cleft remnant. | *[[AKA]] ''branchial cleft remnant''. | ||
===General=== | ===General=== | ||
*Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref> | *Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref> | ||
*Most common cystic neck lesion in young adults.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref> | |||
*Treatment: excision. | *Treatment: excision. | ||
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Features: | Features: | ||
*Cystic space lined by squamous epithelium - usually. | *Cystic space lined by squamous epithelium - usually. | ||
**+/-Inflammation. | |||
*Connective tissue: | *Connective tissue: | ||
**+/-Adipose tissue. | **+/-Adipose tissue. | ||
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**+/-Bone. | **+/-Bone. | ||
**+/-Muscle. | **+/-Muscle. | ||
DDx: | |||
*Cystic [[squamous cell carcinoma]] - may be deceptively benign appearing.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref> | |||
Image: | Image: | ||
*[http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/images%2FB403.jpg Branchial cleft cyst (med.ohio-state.edu)].<ref>URL: [http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/RSLdx.asp http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/RSLdx.asp]. Accessed on: 15 March 2011.</ref> | *[http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/images%2FB403.jpg Branchial cleft cyst (med.ohio-state.edu)].<ref>URL: [http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/RSLdx.asp http://www.pathology.med.ohio-state.edu/residents/InternalGate/Area51/ResidentSlideCollection/RSLdx.asp]. Accessed on: 15 March 2011.</ref> | ||
===IHC=== | |||
*p16 -ve. | |||
**May be done to exclude a [[Human papillomavirus-associated head and neck squamous cell carcinoma]]. | |||
*Ki-67 low. | |||
==Benign lymphoepithelial lesion== | ==Benign lymphoepithelial lesion== | ||