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Difference between revisions of "Endometrial carcinoma"
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→Clear cell carcinoma of the endometrium: +IHC
| Line 162: | Line 162: | ||
**Classically clear cells... but not always. | **Classically clear cells... but not always. | ||
*Hobnail pattern -- apical cytoplasm > cytoplasm on basement membrane. | *Hobnail pattern -- apical cytoplasm > cytoplasm on basement membrane. | ||
===IHC=== | |||
Features:<ref name=Ref_GP250>{{Ref GP|250}}</ref> | |||
*p53 -ve usu. - unlike [[uterine serous carcinoma]]. | |||
*ER -ve. | |||
*PR -ve. | |||
Note: | |||
*HNF1beta - not useful<ref name=pmid22495362>{{Cite journal | last1 = Fadare | first1 = O. | last2 = Liang | first2 = SX. | title = Diagnostic Utility of Hepatocyte Nuclear Factor 1-Beta Immunoreactivity in Endometrial Carcinomas: Lack of Specificity For Endometrial Clear Cell Carcinoma. | journal = Appl Immunohistochem Mol Morphol | volume = | issue = | pages = | month = Apr | year = 2012 | doi = 10.1097/PAI.0b013e31824973d1 | PMID = 22495362 }}</ref> - unlike for [[ovarian clear cell carcinoma]]. | |||
=See also= | =See also= | ||