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Difference between revisions of "Anemia"
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→Pernicious anemia
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*Autoimmune - leads to loss of parietal cells. | *Autoimmune - leads to loss of parietal cells. | ||
**Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''. | **Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''. | ||
Diagnosis - serology for antibodies to:<ref name=pmid12643357>{{Cite journal | last1 = Oh | first1 = R. | last2 = Brown | first2 = DL. | title = Vitamin B12 deficiency. | journal = Am Fam Physician | volume = 67 | issue = 5 | pages = 979-86 | month = Mar | year = 2003 | doi = | PMID = 12643357 }}</ref> | |||
*Parietal cell. | |||
*Iintrinsic factor. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Loss of parietal cells. | *Loss of parietal cells. | ||
=See also= | =See also= | ||
*[[Sickle cell anemia]]. | *[[Sickle cell anemia]]. | ||