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Difference between revisions of "Heart"
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→Coronary artery atherosclerosis
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==Coronary artery atherosclerosis== | ==Coronary artery atherosclerosis== | ||
{{Main| | {{Main|Atherosclerosis}} | ||
*[[AKA]] ''coronary artery disease''. | |||
===General=== | |||
*Greater than 75% (diameter) stenosis - considered significant.<ref>Chamberlain. March 7, 2008.</ref> | *Greater than 75% (diameter) stenosis - considered significant.<ref>Chamberlain. March 7, 2008.</ref> | ||
*Leading cause of morbidity and mortality, esp. in the elderly. | |||
Stenosis definition (as per NASCET):<ref name="pmid9811916">{{cite journal |author=Barnett HJ, Taylor DW, Eliasziw M, ''et al.'' |title=Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators |journal=The New England Journal of Medicine |volume=339 |issue=20 |pages=1415–25 |year=1998 |month=November |pmid=9811916 |doi= |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=9811916&promo=ONFLNS19}}</ref><br> | Note: | ||
*It is '''not''' the only type of ''coronary artery disease''... but the most common. | |||
====Stenosis definition==== | |||
Definition (as per NASCET):<ref name="pmid9811916">{{cite journal |author=Barnett HJ, Taylor DW, Eliasziw M, ''et al.'' |title=Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators |journal=The New England Journal of Medicine |volume=339 |issue=20 |pages=1415–25 |year=1998 |month=November |pmid=9811916 |doi= |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=9811916&promo=ONFLNS19}}</ref><br> | |||
<math>percent\ stenosis = ( 1 - ( minimal\ diameter ) / ( poststenotic\ diameter ) ) x 100%.</math> | <math>percent\ stenosis = ( 1 - ( minimal\ diameter ) / ( poststenotic\ diameter ) ) x 100%.</math> | ||
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*A 75% diameter reduction results in a 93.75% area reduction. | *A 75% diameter reduction results in a 93.75% area reduction. | ||
*A 90% diameter reduction results in a 99% area reduction. | *A 90% diameter reduction results in a 99% area reduction. | ||
===Microscopic=== | |||
:See ''[[atherosclerosis]]''. | |||
==Abnormal hearts== | ==Abnormal hearts== | ||