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Difference between revisions of "Pulmonary cytopathology"
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→Malignant melanoma
(→Squamous cell carcinoma: re-arr to well-diff and poorly diff) |
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==Malignant melanoma== | ==Malignant melanoma== | ||
{{Main|Malignant melanoma}} | |||
===Cytology=== | |||
Classic features: | Classic features: | ||
#Loosely cohesive cells and single cells. | #Loosely cohesive cells and single cells. | ||
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#The classic appearance of melanoma without pigment is closest to adenocarcinoma (which may have red nucleoli, large cells, abundant cytoplasm, occasional binucleation). | #The classic appearance of melanoma without pigment is closest to adenocarcinoma (which may have red nucleoli, large cells, abundant cytoplasm, occasional binucleation). | ||
#*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | #*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | ||
#Bug-eyed monster cells - may vaguely resemble a Reed-Sternberg cell (RSC) - diagnostic of Hodgkin's lymphoma (HL). | #Bug-eyed monster cells - may vaguely resemble a Reed-Sternberg cell (RSC) - diagnostic of [[Hodgkin's lymphoma]] (HL). | ||
#*RSCs do not have the granular cytoplasm typical of melanoma. | #*RSCs do not have the granular cytoplasm typical of melanoma. | ||
#*Nuclei usually adjacent, i.e. not at opposite poles of the cell. | #*Nuclei usually adjacent, i.e. not at opposite poles of the cell. | ||