Difference between revisions of "An introduction to head and neck pathology"

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==Clinical==
==Clinical==
===Oral lesions===
Common lesions:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
DDx:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
*Leukoplakia.
*Leukoplakia.
**Homogeneous.
**Homogeneous.
**Non-homogeneous.
**Non-homogeneous.
*Erythroplakia.
*Erythroplakia - more worrisome for cancer than leukoplakia.


====Leukoplakia====
===Leukoplakia===
Features:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
Features:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
*Unidentified white lesion.
*Unidentified white lesion.
*Often associated with epithelial thickening ([[hyperkeratosis]], acanthosis).
*Often associated with epithelial thickening ([[hyperkeratosis]], acanthosis).
*More worrisome than erythroplakia.
*In twos series ~13% were associated with an invasive lesion.<ref name=pmid19953947>{{Cite journal  | last1 = Lan | first1 = AX. | last2 = Guan | first2 = XB. | last3 = Sun | first3 = Z. | title = [Analysis of risk factors for carcinogenesis of oral leukoplakia]. | journal = Zhonghua Kou Qiang Yi Xue Za Zhi | volume = 44 | issue = 6 | pages = 327-31 | month = Jun | year = 2009 | doi =  | PMID = 19953947 }}</ref><ref name=pmid16545712>{{Cite journal  | last1 = Lee | first1 = JJ. | last2 = Hung | first2 = HC. | last3 = Cheng | first3 = SJ. | last4 = Chen | first4 = YJ. | last5 = Chiang | first5 = CP. | last6 = Liu | first6 = BY. | last7 = Jeng | first7 = JH. | last8 = Chang | first8 = HH. | last9 = Kuo | first9 = YS. | title = Carcinoma and dysplasia in oral leukoplakias in Taiwan: prevalence and risk factors. | journal = Oral Surg Oral Med Oral Pathol Oral Radiol Endod | volume = 101 | issue = 4 | pages = 472-80 | month = Apr | year = 2006 | doi = 10.1016/j.tripleo.2005.07.024 | PMID = 16545712 }}</ref>
**In twos series ~13% were associated with an invasive lesion.<ref name=pmid19953947>{{Cite journal  | last1 = Lan | first1 = AX. | last2 = Guan | first2 = XB. | last3 = Sun | first3 = Z. | title = [Analysis of risk factors for carcinogenesis of oral leukoplakia]. | journal = Zhonghua Kou Qiang Yi Xue Za Zhi | volume = 44 | issue = 6 | pages = 327-31 | month = Jun | year = 2009 | doi =  | PMID = 19953947 }}</ref><ref name=pmid16545712>{{Cite journal  | last1 = Lee | first1 = JJ. | last2 = Hung | first2 = HC. | last3 = Cheng | first3 = SJ. | last4 = Chen | first4 = YJ. | last5 = Chiang | first5 = CP. | last6 = Liu | first6 = BY. | last7 = Jeng | first7 = JH. | last8 = Chang | first8 = HH. | last9 = Kuo | first9 = YS. | title = Carcinoma and dysplasia in oral leukoplakias in Taiwan: prevalence and risk factors. | journal = Oral Surg Oral Med Oral Pathol Oral Radiol Endod | volume = 101 | issue = 4 | pages = 472-80 | month = Apr | year = 2006 | doi = 10.1016/j.tripleo.2005.07.024 | PMID = 16545712 }}</ref>
**Non-homogenous leukoplakia has a greater risk of malignancy than homogenous.<ref name=pmid16545712/>
***Non-homogenous leukoplakia has a greater risk of malignancy than homogenous.<ref name=pmid16545712/>


====Erythroplakia====
===Erythroplakia===
Features:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
Features:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref>
*Unidentified red lesion.
*Unidentified red lesion.
*Often erosion.
*Often erosion.
*Strong association with non-keratinizing squamous lesions (invasive and dysplastic).


=Benign cystic lesions=
=Benign cystic lesions=
48,830

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