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Difference between revisions of "Pediatric gastrointestinal pathology"
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Pediatric gastrointestinal pathology (view source)
Revision as of 04:24, 3 April 2012
, 04:24, 3 April 2012→Aganglionosis: +gross
(→Aganglionosis: +IHC, expand) |
(→Aganglionosis: +gross) |
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Notes: | Notes: | ||
*Most common reason for litigation in paediatric pathology.<ref>GT. 19 January 2011.</ref> | *Most common reason for litigation in paediatric pathology.<ref>GT. 19 January 2011.</ref> | ||
===Gross=== | |||
Features: | |||
*Dilated bowel; stuffed sausage-look. | |||
Image: | |||
*[http://www.pathology.pitt.edu/lectures/gi/colon-a/03.htm Hirschsprung disease (pathology.pitt.edu)]. | |||
===Microscopic=== | ===Microscopic=== | ||
| Line 99: | Line 106: | ||
*Ganglion cells missing in submucosal plexus and myenteric plexus. | *Ganglion cells missing in submucosal plexus and myenteric plexus. | ||
*+/-Submucosal fibrosis. | *+/-Submucosal fibrosis. | ||
Image: | |||
*[http://pathology.mc.duke.edu/research/Histo_course/myent_plexus.jpg Normal myenteric plexus (duke.edu)].<ref>URL: [http://pathology.mc.duke.edu/research/PTH225.html http://pathology.mc.duke.edu/research/PTH225.html]. Accessed on: 11 January 2011.</ref> | |||
===Stains=== | ===Stains=== | ||
| Line 113: | Line 123: | ||
*NSE ~ normal. | *NSE ~ normal. | ||
*S100 ~ normal. | *S100 ~ normal. | ||
==Meconium ileus== | ==Meconium ileus== | ||