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Difference between revisions of "Medical kidney diseases"
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→Fibrillary glomerulonephritis: + immunotactoid glomerulopathy
(→Fibrillary glomerulonephritis: + immunotactoid glomerulopathy) |
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| Line 1,062: | Line 1,062: | ||
===Light chain deposition=== | ===Light chain deposition=== | ||
*Usually associated with kappa clone. | *Usually associated with kappa clone. | ||
==Immunotactoid glomerulopathy== | |||
===General=== | |||
*Uncommon. | |||
*Thought to be a primary glomerulopathy. | |||
**Must exclude [[lupus nephritis]], paraproteinemias, [[fibrillary glomerulopathy]], cryoglobulinemia, [[renal amyloidosis]]. | |||
*Distinct from [[fibrillary glomerulopathy]].<ref name=pmid11961029>{{Cite journal | last1 = Schwartz | first1 = MM. | last2 = Korbet | first2 = SM. | last3 = Lewis | first3 = EJ. | title = Immunotactoid glomerulopathy. | journal = J Am Soc Nephrol | volume = 13 | issue = 5 | pages = 1390-7 | month = May | year = 2002 | doi = | PMID = 11961029 | URL = http://jasn.asnjournals.org/cgi/pmidlookup?view=long&pmid=11961029 }}</ref> | |||
Presentation: | |||
*Nephrotic range proteinuria ~ 60% of cases.<ref>{{Cite journal | last1 = Korbet | first1 = SM. | last2 = Schwartz | first2 = MM. | last3 = Lewis | first3 = EJ. | title = Immunotactoid glomerulopathy. | journal = Am J Kidney Dis | volume = 17 | issue = 3 | pages = 247-57 | month = Mar | year = 1991 | doi = | PMID = 1996564 }}</ref> | |||
*[[Hypertension]]. | |||
===Microscopic=== | |||
Features: | |||
*Mesangial expansion. | |||
DDx: | |||
*Other causes of mesangial expansion. | |||
===IHC=== | |||
*Congo red -ve. | |||
==Fibrillary glomerulonephritis== | ==Fibrillary glomerulonephritis== | ||