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Difference between revisions of "Stomach"
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→Gastric lymphoma
m (→Microscopic) |
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{{main|Lymphoma}} | {{main|Lymphoma}} | ||
===General=== | ===General=== | ||
*Associated with helicobacter infection.<ref name=pmid19273142>{{Cite journal | last1 = Mbulaiteye | first1 = SM. | last2 = Hisada | first2 = M. | last3 = El-Omar | first3 = EM. | title = Helicobacter Pylori associated global gastric cancer burden. | journal = Front Biosci | volume = 14 | issue = | pages = 1490-504 | month = | year = 2009 | doi = | PMID = 19273142 }} | *Associated with helicobacter infection.<ref name=pmid19273142>{{Cite journal | last1 = Mbulaiteye | first1 = SM. | last2 = Hisada | first2 = M. | last3 = El-Omar | first3 = EM. | title = Helicobacter Pylori associated global gastric cancer burden. | journal = Front Biosci | volume = 14 | issue = | pages = 1490-504 | month = | year = 2009 | doi = | PMID = 19273142 }} | ||
</ref> | </ref> | ||
*Usually ''MALT lymphoma'' (mucosa-associated lymphoid tissue lymphoma). | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Sheets of lymphoid cells. | |||
*"Lymphoepithelial lesion" - gastric crypts invaded by a monomorphous population of lymphocytes:<ref>DB. 6 August 2010.</ref> | *"Lymphoepithelial lesion" - gastric crypts invaded by a monomorphous population of lymphocytes:<ref>DB. 6 August 2010.</ref> | ||
*# Cluster of lymphocytes - three cells or more. | **Features: | ||
*#* Single lymphocytes don't count. | **# Cluster of lymphocytes - three cells or more. | ||
*# Clearing around the lymphocyte cluster. | **#* Single lymphocytes don't count. | ||
**# Clearing around the lymphocyte cluster. | |||
**Associated with MALT lymphoma;<ref name=pmid1452124>{{Cite journal | last1 = Papadaki | first1 = L. | last2 = Wotherspoon | first2 = AC. | last3 = Isaacson | first3 = PG. | title = The lymphoepithelial lesion of gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT): an ultrastructural study. | journal = Histopathology | volume = 21 | issue = 5 | pages = 415-21 | month = Nov | year = 1992 | doi = | PMID = 1452124 }}</ref> however, not specific. | |||
===IHC - work-up=== | ===IHC - work-up=== | ||
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Others: | Others: | ||
*CD3, CD20, CD138, kappa, lambda, | *CD3, CD20, CD138, kappa, lambda, BCL2. | ||
===Treatment=== | ===Treatment=== | ||