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(→Classic vulvar intraepithelial neoplasia: +images) |
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==Differentiated vulvar intraepithelial neoplasia== | ==Differentiated vulvar intraepithelial neoplasia== | ||
=== | ===General=== | ||
Epidemiology: | |||
*Associated with [[lichen sclerosus]]. | *Associated with [[lichen sclerosus]]. | ||
*NOT associated with HPV and seen in older women. | *NOT associated with HPV and seen in older women. | ||
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Acanthosis (thickening of stratum spinosum) + elongation of rete ridges. | *Acanthosis (thickening of stratum spinosum) + elongation of rete ridges. | ||
Notes: | |||
*'''Not''' graded like classic VIN. | |||
DDx: | |||
*[[Lichen sclerosus]]. | |||
Images: | |||
*[http://www.nature.com/modpathol/journal/v24/n2/fig_tab/modpathol2010192f3.html#figure-title Differentiated VIN (nature.com)]. | |||
==IHC for VIN== | ==IHC for VIN== |
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