Difference between revisions of "Lung tumours"

Lung tumours (view source)

549 bytes added , 04:11, 4 March 2012

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 ===Molecular===
-*EGFR mutation +ve/-ve.
+*EGFR mutation:
+**Respond to TKI if:<ref name=pmid19680292>{{Cite journal  | last1 = John | first1 = T. | last2 = Liu | first2 = G. | last3 = Tsao | first3 = MS. | title = Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors. | journal = Oncogene | volume = 28 Suppl 1 | issue =  | pages = S14-23 | month = Aug | year = 2009 | doi = 10.1038/onc.2009.197 | PMID = 19680292 }}</ref>
+***Exon 19 deletion.
+***Exon L858R.
 *ALK translocation +ve/-ve.
 *RAS mutation analysis.