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Difference between revisions of "Stomach" - Libre Pathology

Difference between revisions of "Stomach"

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Stomach (view source)

Revision as of 15:16, 2 February 2012

1,063 bytes added ,  15:16, 2 February 2012
m
→‎Gastric lymphoma: more
(→‎Fundic gland polyp: more, may be in the body)
Line 695: Line 695:
**Associated with MALT lymphoma;<ref name=pmid1452124>{{Cite journal  | last1 = Papadaki | first1 = L. | last2 = Wotherspoon | first2 = AC. | last3 = Isaacson | first3 = PG. | title = The lymphoepithelial lesion of gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT): an ultrastructural study. | journal = Histopathology | volume = 21 | issue = 5 | pages = 415-21 | month = Nov | year = 1992 | doi =  | PMID = 1452124 }}</ref> however, not specific.
**Associated with MALT lymphoma;<ref name=pmid1452124>{{Cite journal  | last1 = Papadaki | first1 = L. | last2 = Wotherspoon | first2 = AC. | last3 = Isaacson | first3 = PG. | title = The lymphoepithelial lesion of gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT): an ultrastructural study. | journal = Histopathology | volume = 21 | issue = 5 | pages = 415-21 | month = Nov | year = 1992 | doi =  | PMID = 1452124 }}</ref> however, not specific.


===IHC - work-up===
DDx:
*Reactive lymphoid hyperplasia.
*[[Syphilis]].<ref name=pmid20021615>{{Cite journal  | last1 = Kim | first1 = K. | last2 = Kim | first2 = EJ. | last3 = Kim | first3 = MJ. | last4 = Song | first4 = HJ. | last5 = Lee | first5 = YS. | last6 = Jung | first6 = KW. | last7 = Yu | first7 = E. | title = Clinicopathological features of syphilitic gastritis in Korean patients. | journal = Pathol Int | volume = 59 | issue = 12 | pages = 884-9 | month = Dec | year = 2009 | doi = 10.1111/j.1440-1827.2009.02462.x | PMID = 20021615 }}</ref><ref name=pmid7661178>{{Cite journal  | last1 = Long | first1 = BW. | last2 = Johnston | first2 = JH. | last3 = Wetzel | first3 = W. | last4 = Flowers | first4 = RH. | last5 = Haick | first5 = A. | title = Gastric syphilis: endoscopic and histological features mimicking lymphoma. | journal = Am J Gastroenterol | volume = 90 | issue = 9 | pages = 1504-7 | month = Sep | year = 1995 | doi =  | PMID = 7661178 }}</ref>
 
===IHC===
*Panker -- most useful.
*Panker -- most useful.


Others:
Others:
*CD3, CD20, CD138, kappa, lambda, BCL2.
*CD3 (T cells) - scatter positivity.
*CD20 (B cells) +ve.
*CD138 (plasma cells).
*kappa, lambda -- often one is predominant, suggesting clonality.
*BCL2 +ve.


===Treatment===
===Treatment===
Michael
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