Difference between revisions of "Lymph node pathology"

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***Variable lymphocyte morphology.
***Variable lymphocyte morphology.
***Tingible-body macrophage (large, pale cells with junk in the cytoplasm).
***Tingible-body macrophage (large, pale cells with junk in the cytoplasm).
***Germinal centers (GCs) have a crisp/sharp edge.
***Normal dark/light variation of GCs; superficial aspect light, deeper aspect darker.
**Rim of small (inactive) lymphocytes.
**Rim of small (inactive) lymphocytes.


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Image: [http://pleiad.umdnj.edu/hemepath/normal_node/normal_node.html Normal lymph node (umdnj.edu)].
Image: [http://pleiad.umdnj.edu/hemepath/normal_node/normal_node.html Normal lymph node (umdnj.edu)].
====Follicular lymphoma vs. reactive follicular hyperplasia====
Factors to consider:<ref>DB. 4 August 2010.</ref>
{| class="wikitable"
!
! Reactive follicular hyperplasia
! Follicular lymphoma
|-
| Follicle location
| cortex
| cortex and medulla
|-
| Germinal center edge
| sharp/well-demarcated
| poorly demarcated
|-
| Germinal center density
| well spaced
| crowded
|-
| Tingible body macrophages
| common
| uncommon
|-
| Light/dark pattern
| normal
| abnormal
|}


==Diffuse paracortical hyperplasia==
==Diffuse paracortical hyperplasia==
48,790

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