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==Biopsy size== | ==Biopsy size== | ||
Very small tissue fragments are associated with a decreased diagnostic yield and an increased diagnostic uncertainty. | Very small tissue fragments are associated with a decreased diagnostic yield and an increased diagnostic uncertainty. | ||
==Immunohistochemistry== | |||
A paper by Torlakovic ''et al.''<ref name=pmid20154273>{{Cite journal | last1 = Torlakovic | first1 = EE. | last2 = Riddell | first2 = R. | last3 = Banerjee | first3 = D. | last4 = El-Zimaity | first4 = H. | last5 = Pilavdzic | first5 = D. | last6 = Dawe | first6 = P. | last7 = Magliocco | first7 = A. | last8 = Barnes | first8 = P. | last9 = Berendt | first9 = R. | title = Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee/Immunohistochemistry: best practice recommendations for standardization of immunohistochemistry tests. | journal = Am J Clin Pathol | volume = 133 | issue = 3 | pages = 354-65 | month = Mar | year = 2010 | doi = 10.1309/AJCPDYZ1XMF4HJWK | PMID = 20154273 }}</ref> divides IHC tests into: | |||
*''Class I'': | |||
**Adjunct to histomorphology. | |||
**Example: CD45, S-100. | |||
*''Class II'' - used directly for treatment decisions; it is considered independent of the other information in the pathology report. | |||
**ER, PR, HER2. | |||
==See also== | ==See also== |
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